| Cat. No. |
Product Name |
Information |
| PC-62426 |
SMIFH2
Formin inhibitor
|
SMIFH2 is a small molecule formin homology 2 domains inhibitor of formin-mediated actin assembly, targets formins from evolutionarily diverse organisms including yeast, nematode worm, and mice with IC50s of 5-15 uM. |
| PC-60553 |
MPT0B002
Microtubule inhibitor
|
MPT0B002 is a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. |
| PC-42620 |
Lexibulin dihydrochloride
|
An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
| PC-42619 |
Lexibulin
|
An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
| PC-45982 |
Cephalomannine
|
A taxol derivative with antitumor, antiproliferative properties. |
| PC-42466 |
Ixabepilone
|
A semisynthetic Epothilone B analogue and potent, orally active microtubule stabilizer. |
| PC-45256 |
4|-Demethylepipodophyllotoxin
|
A potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds.. |
| PC-45268 |
Fosbretabulin disodium
|
A derivative of combretastatin that acts as a microtubule destabilising agent. |
| PC-45239 |
Vinblastine
|
A cytotoxic alkaloid that binds tubulin and inhibits the assembly of microtubules. |
| PC-45151 |
Epothilone B
|
A blood-brain barrier-permeable microtubule-stabilizing agent that promotes tubulin polymerization and induces G2-M cell cycle arrest with EC50 of 32 nM in HeLa cells. |
| PC-22650 |
Plecstatin-1 hydrochloride
Plectin inhibitor
|
Plecstatin-1 hydrochloride is a specific ruthenium(arene) pyridinecarbothioamide targeting plectin, affects cytoarchitecture and shape of keratinocytes, inhibits tumor invasiveness. |
| PC-22649 |
Plecstatin-1
Plectin inhibitor
|
Plecstatin-1 is a specific ruthenium(arene) pyridinecarbothioamide targeting plectin, affects cytoarchitecture and shape of keratinocytes, inhibits tumor invasiveness. |
