| Cat. No. |
Product Name |
Information |
| PC-38550 |
Todalam
Tubulin inhibitor
|
Todalam is a novel small molecule tubulin inhibitor with IC50 of 8.8 uM against HeLa cells, fully inhibits microtubule formation with IC50 of 48 uM, acting as a reversible microtubule-destabilizing agent in vitro and in cells. |
| PC-72562 |
Microtubule inhibitor PP-13
Microtubule inhibitor
|
Microtubule inhibitor PP-13 is a novel microtubule-destabilizing agent, directly inhibits microtubule assembly by targeting the colchicine-binding site in β-tubulin. |
| PC-72275 |
IMB5476
Microtubule inhibitor
|
IMB5476 (IMB 5476) is a nitrobenzoate microtubule inhibitor, exerts broad-spectrum cytotoxicity against various human tumor cell lines (NCI-H460, IC50=144 nM). |
| PC-72173 |
PST-3
Microtubule inhibitor
|
PST-3 (Microtubule inhibitor PST-3) is a novel microtubule inhibitor exhibited broad-spectrum cellular cytotoxicity and in vivo potency with high safety. |
| PC-38002 |
PCH-1
Tubulin inhibitor
|
PCH-1 is a potent antitumor agent that disrupts microtubule assembly, leading to cancer cell death, interacts vinblastine binding site on tubulin. |
| PC-36086 |
Avanbulin
Tubulin inhibitor
|
Avanbulin (BAL27862, BAL-27862) is a novel microtubule-destabilizing agent that potently inhibits tubulin assembly at 37°C with IC50 of 1.4 uM in tubulin-binding assays. |
| PC-35925 |
TR-100
Tropomyosin inhibitor
|
TR-100 (TR100) is a specific anti-tropomyosin compound that disrupts the actin cytoskeleton via targeting of Tpm3.1-containing actin filaments. |
| PC-35924 |
ATM-3507
Tropomyosin inhibitor
|
ATM-3507 (ATM3507) is a small molecule inhibitor of Tpm3.1 tropomyosin isoform, disrupts Tpm3.1-containing microfilaments in SK-N-SH cells at 5 uM. |
| PC-35881 |
CCB02
CPAP-tubulin inhibitor
|
CCB02 (CCB 02) is a specific small molecule inhibitor of CPAP-tubulin interaction with IC50 of 0.689 uM in AlphaScreen assay, selectively binds at the CPAP binding site of tubulin. |
| PC-35822 |
6-MOMIPP
Microtubule inhibitor
|
6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro. |
| PC-35617 |
MP-HJ-1b
Microtubule inhibitor
|
MP-HJ-1b is a novel potent inhibitor of microtubule and tumor cell growth, binds the colchicine pocket at the intra-dimer interface, depolymerizes microtubules and affects spindle formation. |
| PC-35599 |
VERU-111 analogue 13f
Tubulin inhibitor
|
VERU-111 analogue 13f is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities. |
