| Cat. No. |
Product Name |
Information |
| PC-38550 |
Todalam
Tubulin inhibitor
|
Todalam is a novel small molecule tubulin inhibitor with IC50 of 8.8 uM against HeLa cells, fully inhibits microtubule formation with IC50 of 48 uM, acting as a reversible microtubule-destabilizing agent in vitro and in cells. |
| PC-72562 |
Microtubule inhibitor PP-13
Microtubule inhibitor
|
Microtubule inhibitor PP-13 is a novel microtubule-destabilizing agent, directly inhibits microtubule assembly by targeting the colchicine-binding site in β-tubulin. |
| PC-72275 |
IMB5476
Microtubule inhibitor
|
IMB5476 (IMB 5476) is a nitrobenzoate microtubule inhibitor, exerts broad-spectrum cytotoxicity against various human tumor cell lines (NCI-H460, IC50=144 nM). |
| PC-72173 |
PST-3
Microtubule inhibitor
|
PST-3 (Microtubule inhibitor PST-3) is a novel microtubule inhibitor exhibited broad-spectrum cellular cytotoxicity and in vivo potency with high safety. |
| PC-38002 |
PCH-1
Tubulin inhibitor
|
PCH-1 is a potent antitumor agent that disrupts microtubule assembly, leading to cancer cell death, interacts vinblastine binding site on tubulin. |
| PC-36086 |
Avanbulin
Tubulin inhibitor
|
Avanbulin (BAL27862, BAL-27862) is a novel microtubule-destabilizing agent that potently inhibits tubulin assembly at 37°C with IC50 of 1.4 uM in tubulin-binding assays. |
| PC-35925 |
TR-100
Tropomyosin inhibitor
|
TR-100 (TR100) is a specific anti-tropomyosin compound that disrupts the actin cytoskeleton via targeting of Tpm3.1-containing actin filaments. |
| PC-35881 |
CCB02
CPAP-tubulin inhibitor
|
CCB02 (CCB 02) is a specific small molecule inhibitor of CPAP-tubulin interaction with IC50 of 0.689 uM in AlphaScreen assay, selectively binds at the CPAP binding site of tubulin. |
| PC-35822 |
6-MOMIPP
Microtubule inhibitor
|
6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro. |
| PC-35617 |
MP-HJ-1b
Microtubule inhibitor
|
MP-HJ-1b is a novel potent inhibitor of microtubule and tumor cell growth, binds the colchicine pocket at the intra-dimer interface, depolymerizes microtubules and affects spindle formation. |
| PC-35599 |
VERU-111 analogue 13f
Tubulin inhibitor
|
VERU-111 analogue 13f is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities. |
| PC-35597 |
VERU-111
Tubulin inhibitor
|
VERU-111 (Sabizabulin, VERU111) is an oral cytoskeleton disruptor that targets and inhibits microtubules to disrupt androgen receptor transport into the nucleus, shows broad antiviral activity by disrupting the intracellular transport of viruses such as SARS CoV-2. |
