| Cat. No. |
Product Name |
Information |
| PC-23057 |
EDP-938
RSV N protein inhibitor
|
Zelicapavir (EDP-938) is a potent RSV viral nucleoprotein (N) inhibitor of both RSV-A and RSV-B activity, inhibits RSV induced CPE with EC50 of 52 nM in HEp-2 cells. |
| PC-21284 |
JNJ-8003
RSV polymerase inhibitor
|
JNJ-8003 is a highly potent, selective, non-nucleoside inhibitor of respiratory syncytial virus (RSV) polymerase with IC50 of 0.67 nM, shows EC50 of 0.15 nM in RSV subgenomic replicon assays. |
| PC-47082 |
AVG-388
RSV RdRP inhibitor
|
AVG-388 is a potent, allosteric, orally efficacious inhibitor of respiratory syncytial virus (RSV) RNA synthesis, potently blocks RSV RNA-dependent RNA polymerase (RdRP) bioactivity, exhibits strong antiviral efficacy in vivo. |
| PC-73390 |
GHP-88309
Paramyxovirus inhibitor
|
GHP-88309 (GHP88309) is a non-nucleoside, broad-spectrum allosteric inhibitor of paramyxovirus polymerase with EC50 of 0.9 uM against HPIV3-JS RdRP. |
| PC-73389 |
JMN3-003
Myxovirus inhibitor
|
JMN3-003 is a host-directed inhibitor with potent antiviral activity against a panel of myxovirus family members with EC50 of 10-70 nM. |
| PC-73388 |
ZHAWOC9045
Paramyxovirus inhibitor
|
ZHAWOC9045 (F2205-0189) is a potent, host-specific small-molecule inhibitor of paramyxovirus (Canine distemper virus, CDV IC50=0.7 uM) and pneumovirus (RSV, IC50=5.9 uM) replication. |
| PC-73387 |
ZHAWOC21026
Paramyxovirus inhibitor
|
ZHAWOC21026 is a highly potent, host-specific small-molecule inhibitor of paramyxovirus (Canine distemper virus, CDV IC50=3.2 nM) and pneumovirus (RSV, IC50=31 nM) replication. |
| PC-36105 |
Ziresovir
RSV F protein inhibitor
|
Ziresovir (RO-0529, AK0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion protein (RSV F protein) inhibitor, shows anti-RSV activity (EC50=3 nM). |
| PC-35776 |
AVG-233
RSV RdRp inhibitor
|
AVG-233 (AVG233) is a potent, allosteric inhibitor of respiratory syncytial virus (RSV) RNA-dependent RNA polymerase (RdRp) complex, demonstrates nanomolar activity against both laboratory-adapted RSV strains and clinical RSV isolates (EC50=34-79 nM). |
| PC-35761 |
RSV inhibitor compound 1
RSV fusion inhibitor
|
RSV inhibitor compound 1 is a novel potent, orally bioavailable RSV fusion inhibitor with EC50 of 2 nM (RSV Long strain infected HEp-2 cells) without significant cytotoxicity (CC50>100 uM). |
| PC-63296 |
Sisunatovir
|
RV521 (Sisunatovir) is a potent, orally active, small-molecule inhibitor of RSV fusion with IC50 of 1.4 nM and 1.0 nM for clinical isolates of RSV-A and RSV-B viruses. |
| PC-43309 |
RSV604
RSV inhibitor
|
RSV604 (RSV-604) is a potent respiratory syncytial virus (RSV) inhibitor with EC50 of 0.86 uM in XTT assay, targets the nucleocapsid protein and is active post-RSV infection. |
