| Cat. No. |
Product Name |
Information |
| PC-43307 |
ALS-8176
RSV polymerase inhibitor
|
ALS-8176 (Lumicitabine) is the 3',5'-di-O-isobutyryl prodrug of ALS-8112 5'-triphosphate (ALS-8112-TP), which is a potent, selective RSV polymerase inhibitor with IC50 of 20 nM. |
| PC-43306 |
ALS-8112
RSV polymerase inhibitor
|
ALS-8112 is a potent, selective RSV polymerase inhibitor, the 5'-triphosphate of ALS-8112 (ALS-8112-TP) inhibits RSV polymerase (IC50=20 nM) without appreciable inhibition of human DNA and RNA polymerases. |
| PC-61493 |
JNJ-53718678
|
JNJ-53718678 (JNJ53718678, JNJ-678) is a potent (Kd=7.4 nM), small-molecule inhibitor of the F-glycoprotein-mediated complex membrane fusion process of the RSV. |
| PC-60362 |
YM-53403
RSV inhibitor
|
YM-53403 (YM53403) is a specific anti-respiratory syncytial virus (RSV) agent with EC50 of 0.2 uM in plaque reduction assays. |
| PC-60361 |
BI Compound D
RSV L-protein polymerase inhibitor
|
BI Compound D is a potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM. |
| PC-60359 |
AZ-27
RSV inhibitor
|
AZ-27 (AZ27) is a potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively. |
| PC-60358 |
PC786
RSV inhibitor
|
PC786 (PC-786) is a potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 2.1 nM and 0.5 nM in cell-free enzyme assay and mini-genome assay in HEp-2 cells, respectively. |
| PC-45063 |
Presatovir
|
Presatovir (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor with mean EC50 of 0.43 nM against a panel of 75 RSV A and B clinical isolates. |
| PC-23259 |
MRK-1
RSV L-protein polymerase inhibitor
|
MRK-1 is a small molecule non-nucleoside inhibitor of the RSV L polymerase protein, binds to the RNA-dependent RNA polymerase (RdRp, L-polymerase) and inhibits vRNA synthesis initiation. |
| PC-22550 |
PAV-431
Viral assembly modulator
|
PAV-431 is a small molecule pan-respiratory viral assembly modulator with EC50 of <100 nM against multiple viruses in cell culture, directly binds to host protein 14-3-3. |
| PC-22419 |
JNJ-7184
RSV inhibitor
|
JNJ-7184 is a potent, selective and non-nucleoside inhibitor of RSV-Large (L) polymerase, displays potent inhibition of both RSV-A and -B strains with EC50 of 13 and 72 nM in vitro. |
| PC-63344 |
Enzaplatovir
|
Enzaplatovir (BTA-585, BTA-C585) is an orally bioavailable RSV fusion protein inhibitor for the treatment of respiratory syncytial virus infections.. |
