| Cat. No. |
Product Name |
Information |
| PC-47082 |
AVG-388
RSV RdRP inhibitor
|
AVG-388 is a potent, allosteric, orally efficacious inhibitor of respiratory syncytial virus (RSV) RNA synthesis, potently blocks RSV RNA-dependent RNA polymerase (RdRP) bioactivity, exhibits strong antiviral efficacy in vivo. |
| PC-73388 |
ZHAWOC9045
Paramyxovirus inhibitor
|
ZHAWOC9045 (F2205-0189) is a potent, host-specific small-molecule inhibitor of paramyxovirus (Canine distemper virus, CDV IC50=0.7 uM) and pneumovirus (RSV, IC50=5.9 uM) replication. |
| PC-36105 |
Ziresovir
|
Ziresovir (AK-0529, AK0529) is a novel RSV F-protein inhibitor for treatment of Hospitalized Respiratory Syncytial Virus (RSV) fnfection. |
| PC-35776 |
AVG-233
RSV inhibitor
|
AVG-233 (AVG233) is a potent, allosteric inhibitor of respiratory syncytial virus (RSV) RNA-dependent RNA polymerase (RdRp) complex, demonstrates nanomolar activity against both laboratory-adapted RSV strains and clinical RSV isolates (EC50=34-79 nM). |
| PC-63296 |
Sisunatovir
|
RV521 (Sisunatovir) is a potent, orally active, small-molecule inhibitor of RSV fusion with IC50 of 1.4 nM and 1.0 nM for clinical isolates of RSV-A and RSV-B viruses. |
| PC-43306 |
ALS-8112
RSV polymerase inhibitor
|
ALS-8112 is a potent, selective RSV polymerase inhibitor, the 5'-triphosphate of ALS-8112 (ALS-8112-TP) inhibits RSV polymerase (IC50=20 nM) without appreciable inhibition of human DNA and RNA polymerases. |
| PC-61493 |
JNJ-53718678
|
JNJ-53718678 (JNJ53718678, JNJ-678) is a potent (Kd=7.4 nM), small-molecule inhibitor of the F-glycoprotein-mediated complex membrane fusion process of the RSV. |
| PC-60362 |
YM-53403
|
YM-53403 (YM53403) is a specific anti-respiratory syncytial virus (RSV) agent with EC50 of 0.2 uM in plaque reduction assays. |
| PC-60359 |
AZ-27
RSV L-protein polymerase inhibitor
|
AZ-27 (AZ27) is a potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively. |
| PC-60358 |
PC786
RSV L-protein polymerase inhibitor
|
PC786 (PC-786) is a potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 2.1 nM and 0.5 nM in cell-free enzyme assay and mini-genome assay in HEp-2 cells, respectively. |
| PC-45063 |
Presatovir
|
Presatovir (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor with mean EC50 of 0.43 nM against a panel of 75 RSV A and B clinical isolates. |
| PC-21284 |
JNJ-8003
RSV polymerase inhibitor
|
JNJ-8003 is a highly potent, selective, non-nucleoside inhibitor of respiratory syncytial virus (RSV) polymerase with IC50 of 0.67 nM, shows EC50 of 0.15 nM in RSV subgenomic replicon assays. |
