| Cat. No. |
Product Name |
Information |
| PC-22014 |
M4K2304
ALK2 inhibitor
|
M4K2304 is a potent, selective BMP type I receptor ALK2 inhibitor with IC50 of 3 nM, >800-fold selective over ALK5. |
| PC-21885 |
SRI-35241
TGF-β inhibitor
|
SRI-35241 is a potent inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.12 nM, 79% inhibition at 100 nM. |
| PC-21884 |
SRI-31277
TGF-β inhibitor
|
SRI-31277 is a tripeptide inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.28 nM. |
| PC-49752 |
Ki26894
TβR-I kinase inhibitor
|
Ki26894 (Ki 26894) is a small molecule TGF-beta type I receptor (TbetaR-I) kinase inhibitor, inhibits TGF-β-induced transcriptional activation in MDA-231-D-TβFluc/Rluc cells with IC50 of 0.49 uM. |