| Cat. No. |
Product Name |
Information |
| PC-62341 |
BRD 9876
Eg5 inhibitor
|
BRD 9876 is an ATP- and ADP-competitive Eg5 (kinesin-5) inhibitor with Ki of 4 nM, selectively inhibits microtubule-bound Eg5 and inhibits multiple myeloma cell growth (IC50=2.2 uM). |
| PC-62340 |
S-Trityl-L-cysteine
Eg5 inhibitor
|
S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM). |
| PC-62339 |
PVZB1194
KSP inhibitor
|
PVZB1194 is a bis(hetero)aryl derivative that inhibits kinesin spindle protein (KSP) ATPase witn IC50 of 0.12 uM. |
| PC-62338 |
MK-0731
KSP inhibitor
|
MK-0731 is a potent, selective kinesin spindle protein (KSP) inhibitor with IC50 of 2.2 nM, cell EC50 of 5.3 nM. |
| PC-62337 |
MK-8267
KSP inhibitor
|
MK-8267 (SCH 2047069) is a potent, orally bioavailable, brain penetrant kinesin spindle protein (KSP) inhibitor with EC50 of 3 nM. |
| PC-62336 |
GSK-1
KSP inhibitor
|
GSK-1 is an ATP-competitive inhibitor of the mitotic kinesin KSP with HCT116 cell IC50 of 36 nM. |
| PC-70048 |
CK-0106023
KSP inhibitor
|
CK-0106023 (CK0106023) is a potent, specific, allosteric inhibitor of KSP motor domain ATPase with Ki of 12 nM. |
| PC-70047 |
HR22C16
Eg5 inhibitor
|
HR22C16 (Monastroline) is a potent, selective and cell permeable inhibitor of mitotic kinesin Eg5 with IC50 of 0.8 uM, does not interact with other microtubule motor proteins. |
| PC-42514 |
GSK-923295
CENP-E inhibitor
|
GSK-923295 (GSK923295) is the first potent, allosteric inhibitor of CENP-E kinesin motor ATPase activity with Ki of 3.2 nM. |
| PC-42308 |
Monastrol
Eg5 inhibitor
|
Monastrol is a potent, specific, allosteric and reversible mitotic kinesin Eg5 inhibitor with IC50 of 14 uM (microtubule motility inhibition). |
| PC-45861 |
Ispinesib
Eg5 inhibitor
|
Ispinesib (SB-715992) is a potent, selective, cell-permeable, allosteric inhibitor of Eg5 (mitotic kinesin KSP) with Ki of 2.3 nM. |
| PC-22245 |
KIF18A inhibitor compound 3
Kif18A inhibitor
|
KIF18A inhibitor compound 3 is a potent, selective mitotic kinesin KIF18A inhibitor of IC50 of 8.2 nM, inhibits KIF18A's microtubule-stimulated ATPase activity. |
