| Cat. No. |
Product Name |
Information |
| PC-42948 |
PI-1840
Proteasome inhibitor
|
PI-1840 is a potent, selective, noncovalent, reversible inhibitor for proteasome chymotrypsin-like (CT-L) activity with IC50 of 27 nM, shows no effect on trypsin-like and peptidylglutamyl peptide hydrolyzing activities (IC50>100 uM). |
| PC-42896 |
Oprozomib
Proteasome inhibitor
|
Oprozomib (ONX-0912, PR-047) is a potent, orally bioavailable proteasome inhibitor that inhibits chymotrypsin-like (CT-L) activity of 20S proteasome β5/LMP7 with IC50 of 36/82 nM. |
| PC-61352 |
o-Phenanthroline
Rpn11 inhibitor
|
o-Phenanthroline is a selective inhibitor of 26S proteasome subunit Rpn11 with IC50 of 10±2 uM. |
| PC-61315 |
Marizomib
20S proteasome inhibitor
|
Marizomib (NPI 0052, Salinosporamide A) is a potent, orally bioactive 20S proteasome inhibitor with IC50 of 1.3 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity). |
| PC-61314 |
Omuralide
20S proteasome inhibitor
|
Omuralide (Clasto-lactacystin) is a potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity). |
| PC-61193 |
CSN5i-3
CSN5 inhibitor
|
CSN5i-3 (CSN5 inhibitor 3) is a potent, selective and orally available inhibitor of CSN5 with IC50 of 5.8 nM, the proteolytic subunit of COP9 signalosome (CSN). |
| PC-61132 |
Rpn11 inhibitor 35
|
Rpn11 inhibitor 35 is a potent, small molecule inhibitor of the proteasome subunit Rpn11 with IC50 of 400 nM,100-fold selectivity over Csn5 and 10-fold selectivity over AMSH. |
| PC-61131 |
8-Thioquinoline
Rpn11 inhibitor
|
8-Thioquinoline (8TQ) is a potent, small molecule inhibitor of the proteasome subunit Rpn11 with IC50 of 2.5 uM. |
| PC-60971 |
YU-101
Proteasome β5 inhibitor
|
YU-101 is a potent, specific proteasome β5 subunit inhibitor with IC50 of 0.26 uM, 7.3 and 17.3-fold selectivity over β2i and β1i subunit, respecitvely. |
| PC-60970 |
NC-005
Proteasome β5 inhibitor
|
NC-005 is a potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 44 nM, 105 and 225-fold selectivity over β2i and β1i subunit, respecitvely. |
| PC-60969 |
NC-001
Proteasome inhibitor
|
NC-001 (NC 001, NC001, az-NC-001) is a potent, specific, cell-permeable inhibitor of immunoproteasome caspase-like sites (β1i and β1), does not correlate with inhibition of chymotrypsin-like sites. |
| PC-60968 |
ML 604440
Proteasome LMP2 inhibitor
|
ML 604440 (ML604440, ML-604440) is a potent, specific and cell permeable proteasome β1i (LMP2) subunit inhibitor. |
