| Cat. No. |
Product Name |
Information |
| PC-61315 |
Marizomib
20S proteasome inhibitor
|
Marizomib (NPI 0052, Salinosporamide A) is a potent, orally bioactive 20S proteasome inhibitor with IC50 of 1.3 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity). |
| PC-61314 |
Omuralide
20S proteasome inhibitor
|
Omuralide (Clasto-lactacystin) is a potent 20S proteasome inhibitor with IC50 of 49 nM (inhibition of proteasomal chymotrypsin-like proteolytic activity). |
| PC-61193 |
CSN5i-3
CSN5 inhibitor
|
CSN5i-3 (CSN5 inhibitor 3) is a potent, selective and orally available inhibitor of CSN5 with IC50 of 5.8 nM, the proteolytic subunit of COP9 signalosome (CSN). |
| PC-61132 |
Rpn11 inhibitor 35
|
Rpn11 inhibitor 35 is a potent, small molecule inhibitor of the proteasome subunit Rpn11 with IC50 of 400 nM,100-fold selectivity over Csn5 and 10-fold selectivity over AMSH. |
| PC-61131 |
8-Thioquinoline
Rpn11 inhibitor
|
8-Thioquinoline (8TQ) is a potent, small molecule inhibitor of the proteasome subunit Rpn11 with IC50 of 2.5 uM. |
| PC-60971 |
YU-101
Proteasome β5 inhibitor
|
YU-101 is a potent, specific proteasome β5 subunit inhibitor with IC50 of 0.26 uM, 7.3 and 17.3-fold selectivity over β2i and β1i subunit, respecitvely. |
| PC-60970 |
NC-005
Proteasome β5 inhibitor
|
NC-005 is a potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 44 nM, 105 and 225-fold selectivity over β2i and β1i subunit, respecitvely. |
| PC-60969 |
NC-001
Proteasome inhibitor
|
NC-001 (NC 001, NC001, az-NC-001) is a potent, specific, cell-permeable inhibitor of immunoproteasome caspase-like sites (β1i and β1), does not correlate with inhibition of chymotrypsin-like sites. |
| PC-60968 |
ML 604440
Proteasome LMP2 inhibitor
|
ML 604440 (ML604440, ML-604440) is a potent, specific and cell permeable proteasome β1i (LMP2) subunit inhibitor. |
| PC-60966 |
UK-101
LMP2 inhibitor
|
UK-101 is a potent, specific immunoproteasome β1i (LMP2) subunit inhibitor with IC50 of 104 nM, 144- and 10-fold selectivity over β1c and β5 subunit respectivey. |
| PC-60965 |
PR-825
Proteasome β5 inhibitor
|
PR-825 is a potent, specific immunoproteasome β5 subunit inhibitor. |
| PC-60964 |
PR-893
Proteasome inhibitor
|
PR-893 is a potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM, 21-fold and 13-fold selectivity for β5 over LMP7 and LMP2 subunits, respecitvely. |
