| Cat. No. |
Product Name |
Information |
| PC-60966 |
UK-101
LMP2 inhibitor
|
UK-101 is a potent, specific immunoproteasome β1i (LMP2) subunit inhibitor with IC50 of 104 nM, 144- and 10-fold selectivity over β1c and β5 subunit respectivey. |
| PC-60965 |
PR-825
Proteasome β5 inhibitor
|
PR-825 is a potent, specific immunoproteasome β5 subunit inhibitor. |
| PC-60964 |
PR-893
Proteasome inhibitor
|
PR-893 is a potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM, 21-fold and 13-fold selectivity for β5 over LMP7 and LMP2 subunits, respecitvely. |
| PC-60963 |
PR-924
LMP7 inhibitor
|
PR-924 is a potent, specific immunoproteasome LMP7 subunit inhibitor with IC50 of 25 nM, >100-fold selectivity over β5c, β1i, β1c, β2i and β2c subunits (IC50>3 uM). |
| PC-60962 |
KZR-504
LMP2 inhibitor
|
KZR-504 (KZR504) is a potent, highly selective inhibitor of immunoproteasome low molecular polypeptide-2 (LMP2) subunit with IC50 of 51 nM. |
| PC-60898 |
Capzimin
Rpn11 inhibitor
|
Capzimin (Rpn11 inhibitor 3027) is a derivative of 8TQ, and potent and specific inhibitor of proteasome isopeptidase Rpn11 (PSMD14) with IC50 of 0.34 uM, >7-fold improved potency over 8TQ (quinoline-8-thiol). |
| PC-60476 |
FV-162
Proteasome inhibitor
|
FV-162 is a potent, orally bioavailable, irreversible proteasome inhibitor with potent antimyeloma activity (IC50<60 nM). |
| PC-42596 |
Ixazomib
Proteasome inhibitor
|
Ixazomib (MLN2238) is a potent, selective, orally bioavailable proteasome inhibitor with IC50 of 3.4 nM. |
| PC-42595 |
MLN9708
Proteasome inhibitor
|
Ixazomib citrate (MLN9708) is a potent, selective, orally bioavailable proteasome inhibitor with IC50 of 3.4 nM. |
| PC-42470 |
Bortezomib
Proteasome inhibitor
|
Bortezomib (PS341) is a potent, selective, competitive, orally active Proteasome inhibitor with Ki of 0.6 nM for 20S Proteasome. |
| PC-42597 |
Delanzomib
Proteasome inhibitor
|
Delanzomib (CEP18770) is a potent, orally active proteasome inhibitor with IC50 of 3.8 nM against chymotrypsin-like proteasome activity. |
| PC-42598 |
Carfilzomib
Proteasome inhibitor
|
Carfilzomib (PR-171) is a potent, highly selective inhibitor chymotrypsin-like activity of proteasome with IC50 of 6 nM. |
