| Cat. No. |
Product Name |
Information |
| PC-42609 |
AM580
RARα agonist
|
AM580 (CD336, NSC608001, Ro 40-6055) is an analog of retinoic acid that fuctions as a selective RARα agonist with EC50 of 0.3 nM. |
| PC-42316 |
AR7
RARα antagonist, CMA activator
|
AR7 (AR-7, AR 7) is a specific retinoid derivative that functions as a potent antagonist of RARα activity, specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy. |
| PC-27460 |
CD2314
RARβ agonist
|
CD2314 is a potent, selective retinoid acid receptor β (RARβ) agonist with Kd of 195 nM in S91 melanoma cells. |
| PC-26462 |
Adapalene
RAR agonist
|
Adapalene (CD271) is a third-generation synthetic retinoid and potent RAR agonist with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. |
| PC-26026 |
RXR agonist V-125
RXR agonist
|
RXR agonist V-125 is a potent, selective next-generation RXR agonist with EC50 of 14 nM (RXRα activation). |
| PC-25192 |
6OHA
RXR agonist
|
6OHA is a novel retinoid X receptor (RXR) agonist. |
| PC-24819 |
Retinoic acid
RAR agonist
|
Retinoic acid (ATRA) is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis, a natural agonist of RAR nuclear receptors with IC50s of 14 nM for RARα/β/γ. |
| PC-24606 |
Bigelovin
RXR agonist
|
Bigelovin is a sesquiterpene lactone isolated from Inula hupehensis I and selective RXR agonist (EC50=4.9 uM), binds to RXRα-LBD with Kd of 8.7 uM. |
| PC-24540 |
AS4040605
RARα inhibitor
|
AS4040605 is a novel retinoic acid receptor-α (RARα) inhibitor, suppresses IL2+IL33-induced IL-5 production in mouse type 2 innate lymphoid cells (ILC2s) with IC50 of 7.9 nM. |
| PC-23872 |
CBt-PMN
RXR partial agonist
|
CBt-PMN is a potent, selective retinoid X receptor (RXR) partial agonist with EC50 of 143 nM (RXRα, Emax = 75%), behaves similarly toward other RXR subtypes. |
| PC-23687 |
LG100268
RXR agonist
|
LG100268 (LG268) is a potent, selective, orally active retinoid X receptor (RXR) agonist with EC50 of 4 nM, 3 nM, and 4 nM for RXRα, RXRβ, and RXRγ, respectively. |
| PC-21837 |
E6060
RARα agonist
|
E6060 is a potent, selective retinoic acid receptor subtype α (RAR-α) agonist with Ki of 0.2 nM, IC50 of 0.2 nM for RAR-α-mediated reporter transactivation assays. |
