| Cat. No. |
Product Name |
Information |
| PC-24819 |
Retinoic acid
RAR agonist
|
Retinoic acid (ATRA) is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis, a natural agonist of RAR nuclear receptors with IC50s of 14 nM for RARα/β/γ. |
| PC-24606 |
Bigelovin
RXR agonist
|
Bigelovin is a sesquiterpene lactone isolated from Inula hupehensis I and selective RXR agonist (EC50=4.9 uM), binds to RXRα-LBD with Kd of 8.7 uM. |
| PC-24540 |
AS4040605
RARα inhibitor
|
AS4040605 is a novel retinoic acid receptor-α (RARα) inhibitor, suppresses IL2+IL33-induced IL-5 production in mouse type 2 innate lymphoid cells (ILC2s) with IC50 of 7.9 nM. |
| PC-23872 |
CBt-PMN
RXR partial agonist
|
CBt-PMN is a potent, selective retinoid X receptor (RXR) partial agonist with EC50 of 143 nM (RXRα, Emax = 75%), behaves similarly toward other RXR subtypes. |
| PC-23768 |
YCT-529
RARα antagonist
|
YCT-529 is a potent and selective RARα antagonist with IC50 of 6.8 nM, shows no activity against RARβ and RARγ up to 30 uM. |
| PC-23687 |
LG100268
RXR agonist
|
LG100268 (LG268) is a potent, selective, orally active retinoid X receptor (RXR) agonist with EC50 of 4 nM, 3 nM, and 4 nM for RXRα, RXRβ, and RXRγ, respectively. |
| PC-21837 |
E6060
RARα agonist
|
E6060 is a potent, selective retinoic acid receptor subtype α (RAR-α) agonist with Ki of 0.2 nM, IC50 of 0.2 nM for RAR-α-mediated reporter transactivation assays. |
| PC-21834 |
CD2019
RARβ agonist
|
CD2019 is a selective retinoic acid receptor β (RARβ) agonist, CD2019 is 5-fold selective for RARβ over RARα and 12-fold selective for RARβ over RARγ. |
| PC-21833 |
ER-38925
RARα agonist
|
ER-38925 is a potent, selective retinoic acid receptor subtype α (RAR-α) agonist, inhibits proliferation of mouse spleen cells with IC50 of 0.2 nM. |
| PC-21720 |
RXR agonist 33
RXR agonist
|
RXR agonist 33 is a highly potent, selective and partial RXR agonist with EC50 of 9/18/11 nM for RXRα/β/γ respectively. |
| PC-20840 |
BPA-B9
RXRα inhibitor
|
BPA-B9 (Bipyridine amide B9) is a small molecule RXRα-targeted anti-mitotic agent, binds to RXRα (Kd=39 nM) and selectively inhibits the p-RXRα/PLK1 interaction to induce mitotic arrest and catastrophe in cancer cells. |
