| Cat. No. |
Product Name |
Information |
| PC-21836 |
CD666
RARγ agonist
|
CD666 is a potent, selective RARgamma (RARγ) agonist. |
| PC-21835 |
CD2665
RARγ inhibitor
|
CD2665 is a potent, selective and orally active RAR-β/ RAR-γ antagonist with Ki of 306 and 110 nM, respectively. |
| PC-21834 |
CD2019
RARβ agonist
|
CD2019 is a selective retinoic acid receptor β (RARβ) agonist, CD2019 is 5-fold selective for RARβ over RARα and 12-fold selective for RARβ over RARγ. |
| PC-21833 |
ER-38925
RARα agonist
|
ER-38925 is a potent, selective retinoic acid receptor subtype α (RAR-α) agonist, inhibits proliferation of mouse spleen cells with IC50 of 0.2 nM. |
| PC-21720 |
RXR agonist 33
RXR agonist
|
RXR agonist 33 is a highly potent, selective and partial RXR agonist with EC50 of 9/18/11 nM for RXRα/β/γ respectively. |
| PC-21210 |
BMS961
RARgamma agonist
|
BMS961 is a potent, selective retinoic acid receptor-gamma (RARγ) agonist. |
| PC-21164 |
IRX4647
RARγ agonist
|
IRX4647 is a selective RARγ agonist, regulates T cell biology and reduces syngeneic tumor growth of immune checkpoint-resistant lung cancer cell line (344SQ) when combined with anti-PD-L1. |
| PC-21162 |
AGN196996
RARα antagonist
|
AGN 196996 (IRX6696) is a potent selective RARα antagonist with Ki of 2 nM, shows little to no activity against RARβ and RARγ. |
| PC-21041 |
Tamibarotene
RARα agonist
|
Tamibarotene (Am-80, SY-1425) is a potent and selective retinoic acid receptor α (RARα) agonist with high selectivity over RARγ, exhibits anti-angiogenic activity. |
| PC-20840 |
BPA-B9
RXRα inhibitor
|
BPA-B9 (Bipyridine amide B9) is a small molecule RXRα-targeted anti-mitotic agent, binds to RXRα (Kd=39 nM) and selectively inhibits the p-RXRα/PLK1 interaction to induce mitotic arrest and catastrophe in cancer cells. |
| PC-20839 |
XS-060
RXRα inhibitor
|
XS-060 is a small molecule RXRα-targeted anti-mitotic agent, binds to RXRα (Kd=1.3 uM) and selectively inhibits the p-RXRα/PLK1 interaction to induce mitotic arrest and catastrophe in cancer cells. |
| PC-20831 |
PA452
RXR antagonist
|
PA452 is a specific antagonist of retinoic X receptor (RXR) with pA2 value of 7.11. |
