| Cat. No. |
Product Name |
Information |
| PC-42316 |
AR7
|
AR7 (AR-7, AR 7) is a novel retinoid derivative that functions as chemical activator on RARα activity. |
| PC-23768 |
YCT-529
RARα antagonist
|
YCT-529 is a potent and selective RARα antagonist with IC50 of 6.8 nM, shows no activity against RARβ and RARγ up to 30 uM. |
| PC-23687 |
LG100268
RXR agonist
|
LG100268 (LG268) is a potent, selective, orally active retinoid X receptor (RXR) agonist with EC50 of 4 nM, 3 nM, and 4 nM for RXRα, RXRβ, and RXRγ, respectively. |
| PC-23686 |
LG100754
RXR homodimer antagonist
|
LG100754 (UVI 2112) is a specific antagonist of RXR homodimer also functions as a RXR:PPARα and RXR:PPARγ agonist. |
| PC-21837 |
E6060
RARα agonist
|
E6060 is a potent, selective retinoic acid receptor subtype α (RAR-α) agonist with Ki of 0.2 nM, IC50 of 0.2 nM for RAR-α-mediated reporter transactivation assays. |
| PC-21834 |
CD2019
RARβ agonist
|
CD2019 is a selective retinoic acid receptor β (RARβ) agonist, CD2019 is 5-fold selective for RARβ over RARα and 12-fold selective for RARβ over RARγ. |
| PC-21833 |
ER-38925
RARα agonist
|
ER-38925 is a potent, selective retinoic acid receptor subtype α (RAR-α) agonist, inhibits proliferation of mouse spleen cells with IC50 of 0.2 nM. |
| PC-21720 |
RXR agonist 33
RXR agonist
|
RXR agonist 33 is a highly potent, selective and partial RXR agonist with EC50 of 9/18/11 nM for RXRα/β/γ respectively. |
| PC-21210 |
BMS961
RARgamma agonist
|
BMS961 is a potent, selective retinoic acid receptor-gamma (RARγ) agonist. |
| PC-21041 |
Tamibarotene
RARα agonist
|
Tamibarotene (Am-80, SY-1425) is a potent and selective retinoic acid receptor α (RARα) agonist with high selectivity over RARγ, exhibits anti-angiogenic activity. |
| PC-20840 |
BPA-B9
RXRα inhibitor
|
BPA-B9 (Bipyridine amide B9) is a small molecule RXRα-targeted anti-mitotic agent, binds to RXRα (Kd=39 nM) and selectively inhibits the p-RXRα/PLK1 interaction to induce mitotic arrest and catastrophe in cancer cells. |
| PC-20831 |
PA452
RXR antagonist
|
PA452 is a specific antagonist of retinoic X receptor (RXR) with pA2 value of 7.11. |
