| Cat. No. |
Product Name |
Information |
| PC-70295 |
BMS948
RARβ agonist
|
BMS948 is a RARβ-selective agonist that exhibits a full transcriptional agonistic activity and activating RARβ as efficiently as the reference agonist TTNPB. |
| PC-70294 |
BMS-189453
RARβ agonist, RARα/RARγ antagonist
|
BMS-189453 (BMS189453, BMS453) is a synthetic retinoid that acts as an agonist of RARβ and an antagonist of RARα and RARγ. |
| PC-70293 |
BMS493
pan-RAR inverse agonist
|
BMS-204493 (BMS493) is a potent, pan-RAR inverse agonist that blocks RARα activity with IC50 of 114 nM. |
| PC-70292 |
LE-540
RARβ antagonist
|
LE-540 (LE540) is a potent, selective RARβ antagonist that inhibits RA-induced transcriptional activation of RARβ, but not RARα, RARγ or RXRα on a variety of RA response elements. |
| PC-70289 |
CD 1530
RARγ agonist
|
CD 1530 is a potent and selective RARγ receptor agonist with Ki of 150 nM, >10-fold less potent for RARβ and RARα. |
| PC-70288 |
BMS-753
RARα agonist
|
BMS-753 (BMS753) is a potent, specific RARα agonist with Ki of 2 nM, displays no significant effects on RARγ in reporter based assays. |
| PC-70122 |
AGN-195183
RARα agonist
|
AGN-195183 (VTP-195183;NRX-195183, IRX-5183) is a potent, selective RARα agonist with binding Kd of 3 nM. |
| PC-42609 |
AM580
RARα agonist
|
AM580 (CD336, NSC608001, Ro 40-6055) is an analog of retinoic acid that fuctions as a selective RARα agonist with EC50 of 0.3 nM. |
| PC-42316 |
AR7
RARα antagonist, CMA activator
|
AR7 (AR-7, AR 7) is a specific retinoid derivative that functions as a potent antagonist of RARα activity, specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy. |
| PC-26462 |
Adapalene
RAR agonist
|
Adapalene (CD271) is a third-generation synthetic retinoid and potent RAR agonist with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. |
| PC-26026 |
RXR agonist V-125
RXR agonist
|
RXR agonist V-125 is a potent, selective next-generation RXR agonist with EC50 of 14 nM (RXRα activation). |
| PC-25192 |
6OHA
RXR agonist
|
6OHA is a novel retinoid X receptor (RXR) agonist. |
