Sodium Channel (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-23533	NaV1.7 inhibitor 31 Nav1.7 inhibitor	NaV1.7 inhibitor 31 is a potent and selective inhibitor of Nav1.7 with Ki/IC50 of 4.9 nM/13 nM (hNav1.7), >400-fold selective over hNav1.5.
PC-23462	ETD001 ENaC inhibitor	ETD001 is a potent, selective epithelial sodium channel (ENaC) inhibitor with IC50 of 57 nM.
PC-22308	QLS-81 Nav1.7 inhibitor	QLS-81 is a potent, selective Nav1.7 channel inhibitor with IC50 of 3.5 uM for inhibition of Nav1.7 current in whole-cell patch-clamp recording assay.
PC-21839	S3969 ENaC activator	S3969 is a small molecule activator of the human epithelial sodium channel (ENaC) with EC50 of 1.2 uM in ENaC-expressing oocytes.
PC-21779	XPC-5462 NaV1.2/1.6 inhibitor	XPC-5462 is a potent, selective dual inhibitor of NaV1.6 and NaV1.2 with IC50 of 10.9 nM and 10.3 nM, respectively.
PC-21711	UTX-143 NHE5 inhibitor	UTX-143 is a potent, selective sodium-hydrogen exchange subtype 5 (NHE5) inhibitor with IC50 of 3.11 uM, 80-fold selective over NHE1.
PC-21230	Aneratrigine Sodium Channel inhibitor	Aneratrigine is a sodium channel protein type 9 subunit alpha blocker.
PC-20850	DS43260857 NaV1.7 inhibitor	DS43260857 is a potent, selective NaV1.7 inhibitor with IC50 of 15 nM (hNaV1.7), shows 440-fold and 930-fold selectivity over hNaV1.1 and hNaV1.5, respectively.

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