| Cat. No. |
Product Name |
Information |
| PC-21779 |
XPC-5462
NaV1.2/1.6 inhibitor
|
XPC-5462 is a potent, selective dual inhibitor of NaV1.6 and NaV1.2 with IC50 of 10.9 nM and 10.3 nM, respectively. |
| PC-21778 |
XPC-7224
NaV1.6 inhibitor
|
XPC-7224 is a potent, selective NaV1.6 inhibitor with IC50 of 78 nM and 130 nM for human and mouse NaV1.6, respectively, interacts with the inactivated state of the channel. |
| PC-21711 |
UTX-143
NHE5 inhibitor
|
UTX-143 is a potent, selective sodium-hydrogen exchange subtype 5 (NHE5) inhibitor with IC50 of 3.11 uM, 80-fold selective over NHE1. |
| PC-21230 |
Aneratrigine
Sodium Channel inhibitor
|
Aneratrigine is a sodium channel protein type 9 subunit alpha blocker. |
| PC-20850 |
DS43260857
NaV1.7 inhibitor
|
DS43260857 is a potent, selective NaV1.7 inhibitor with IC50 of 15 nM (hNaV1.7), shows 440-fold and 930-fold selectivity over hNaV1.1 and hNaV1.5, respectively. |
| PC-49611 |
A-887826
Nav 1.8 blocker
|
A-887826 (A 887826) is a potent and voltage-dependent Na(v)1.8 sodium channel blocker with IC50 of 11 nM (hNav1.8), potently blocks tetrodotoxin-resistant sodium (TTX-R Na(+)) currents (IC50=8 nM) from small diameter rat DRG neurons. |
| PC-47030 |
BW-031 iodide
Nav1.7 inhibitor
|
BW-031 iodide is a potent cationic sodium channel inhibitor, inhibited Nav 1.7 (IC50=9.5 uM) and Nav 1.1 channels with approximately sixfold greater potency than QX-314. |
| PC-47029 |
BW-031 chloride
Nav1.7 inhibitor
|
BW-031 chloride is a potent cationic sodium channel inhibitor, inhibited Nav 1.7 (IC50=9.5 uM) and Nav 1.1 channels with approximately sixfold greater potency than QX-314. |
| PC-38569 |
DPI 201-106
Na+ channel opener
|
DPI 201-106 (SDZ 201106) is a positive inotropic agent that prolongs the open state of cardiac voltage-gated Na+ channels. |
| PC-38398 |
Idrevloride
ENaC inhibitor
|
Idrevloride is a potent, selective epithelial sodium channel (ENaC) blocker with potential for the treatment of skin disorders. |
| PC-73408 |
Bliretrigine
Sodium Channel inhibitor
|
Bliretrigine is a sodium channel blocker with the effect of relieving pain. |
| PC-73335 |
ASIC1a inhibitor 5b
ASIC1a inhibitor
|
ASIC1a inhibitor 5b is a highly selective and potent ASIC1a inhibitor, inhibits proton-evoked ASIC1a currents with an apparent IC50 of 27 nM at pH 6.7. |
