| Cat. No. |
Product Name |
Information |
| PC-73334 |
Psalmotoxin 1
ASIC1a inhibitor
|
Psalmotoxin 1 (PCTX1) is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker with IC50 of 0.9 nM. |
| PC-72811 |
NaV1.7 inhibitor Compound 194
NaV1.7 inhibitor
|
NaV1.7 inhibitor Compound 194 is a potent and selective inhibitor of NaV1.7 currents in DRG neurons via inhibition of the CRMP2-Ubc9 interaction. |
| PC-72209 |
SSCI-2
Nav1.7 inhibitor
|
SSCI-2 is a highly potent, selective NaV1.7 inhibitor with IC50 of 9 and 17 nM on human and rhesus Nav1.7 channels, respectively. |
| PC-72208 |
SSCI-1
Nav1.7 inhibitor
|
SSCI-1 is a highly potent, selective NaV1.7 inhibitor with IC50 of 27 and 82 nM on human and rhesus Nav1.7 channels, respectively. |
| PC-72207 |
NaV1.7 inhibitor 51
Nav1.7 inhibitor
|
NaV1.7 inhibitor 51 is a highly potent, selective, orally active NaV1.7 inhibitor with IC50 of 10.7 nM in FLIPR membrane potential assay, no significant activity against NaV1.5 (IC50>10 uM). |
| PC-72206 |
ProTx-II
NaV1.7 inhibitor
|
ProTx II (Protoxin II) is a selective NaV1.7 channel blocker with 100-fold selectivity over other sodium channel subtypes. |
| PC-72205 |
DA-0218
Nav1.7 inhibitor
|
DA-0218 (DA0218) is a novel potent, selective Nav1.7 inhibitor, inhibits sodium currents in Nav1.7-expressing human embryonic kidney 293 cells with IC50 of 0.74 uM. |
| PC-43095 |
Tetrodotoxin citrate
|
Tetrodotoxin (TTx) is a potent, highly selective sodium channel blocker with IC50 of 33 nM for Nav1.6. |
| PC-62647 |
Diminazene aceturate
|
Diminazene aceturate is an anti-infective agent, also is a slow pore blocker of acid-sensing ion channel 1a (ASIC1a) with IC50 of 0.3 uM. |
