| Cat. No. |
Product Name |
Information |
| PC-22703 |
TLR2 activator R-7d
TLR2 agonist
|
TLR2 activator R-7d is a highly potent and selective human TLR2 activator with EC50 of 116 pM in human THP-1 cells, promotes TLR1/2-induced NF-κB promoter activation. |
| PC-22592 |
CL264
TLR7 agonist
|
CL264 is a potent, selective toll like receptor 7 (TLR7) agonist and resiquimod analogue. |
| PC-22583 |
PVP-037.1
TLR7/8 agonist
|
PVP-037.1 is a small-molecule that induces cytokine production and TLR7/8 agonist, demonstrates TLR7-dependent enhancement of TH1-polarizing adjuvanticity. |
| PC-22582 |
PVP-037
TLR7/8 agonist
|
PVP-037 is a small-molecule that induces cytokine production, demonstrates TLR7-dependent enhancement of TH1-polarizing adjuvanticity. |
| PC-22146 |
E6446 dihydrochloride
TLR7/TLR9 inhibitor
|
E6446 dihydrochloride is a potent, orally available small molecule inhibitor of TLR7 and TLR9 with IC50 of 1.78 uM and 0.01 uM, respectively. |
| PC-22025 |
GY101
TLR7 agonist
|
GY101 is a potent, selective TLR7 agonist, activates the TLR7/NF-κB signaling pathway with EC50 of 0.15 uM. |
| PC-21750 |
TLR7 agonist 20
TLR7 agonist
|
TLR7 agonist 20 is a potent, selective TLR7 agonist with EC50 of 12 nM and 17 nM for hTLR and mTLR7 in cell-based reporter assay, respectively. |
| PC-21155 |
E104
TLR7 agonist
|
E014 is a potent, selective TLR7 agonist with EC50 of 69 nM in Ramos Blue reporter assays, >500-fold selective for TLR7 over TLR8. |
| PC-21154 |
TLR7 agonist 17b
TLR7 agonist
|
TLR7 agonist 17b is a potent, selective TLR7 agonist with EC50 of 18 nM in Ramos Blue reporter assays, >500-fold selective for TLR7 over TLR8. |
| PC-21103 |
Loxoribine
TLR7 agonist
|
Loxoribine (7-Allyl-8-oxoguanosine, RWJ21757) is a selective Toll-like receptor 7 (TLR7) agonist and immune modulator. |
| PC-73460 |
Polvitolimod
TLR7 agonist
|
Polvitolimod is a toll-like receptor 7 (TLR7) agonist for treatment of cancer and infectious disease. |
