Cat. No. |
Product Name |
Information |
PC-72051 |
TLR789 inhibitor 7f
TLR789 inhibitor
|
TLR789 inhibitor 7f is a potent, orally bioavailable antagonist of Toll-like Receptor 7/8/9 (TLR7/8/9) with IC50 of 10/17/700 nM in NF-kB reporter assays, does not inhibit TLR3/4. |
PC-35315 |
TLR7 and 8 modulator 31
|
TLR7 and 8 modulator 31 is a potent, orally active, dual TLR7 and 8 agonist with LEC values of 0.15 and 0.16 uM, respectively. |
PC-61096 |
TLR9 inhibitor 18
|
A potent, selective TLR9 antagonist with IC50 of 13 nM (human TLR9), displays 75-fold selectivity over TLR7 and no activity against TLR8 (IC50>10 uM). |