| Cat. No. |
Product Name |
Information |
| PC-49127 |
E567
TLR2 inhibitor
|
E567 is a small moleculeTLR2 signaling inhibitor with anti-viral activity, efficiently inhibits both LCMV and HSV-1 induced cytokine responses in both human and mouse cell cultures. |
| PC-49018 |
SMU-Z1
TLR1/2 agonist
|
SMU-Z1 is a potent, specific small molecule agonist of TLR1/2, specifically activates TLR2 through its association with TLR1, induces NF‐κB activation in HEK‐Blue hTLR2 cells with EC50 of 4.88 nM. |
| PC-47088 |
Diprovocim-X
TLR1/TLR2 agonist
|
Diprovocim-X is a potent human and murine TLR1/TLR2 agonist with EC50 of 0.14 nM (hTLR1/TLR2) and 0.75 nM (m TLR1/TLR2), respectively. |
| PC-38500 |
BMS-905
TLR7/TLR8 inhibitor
|
BMS-905 is a potent dual inhibitor of TLR7 and TLR8 with IC50 of 0.3 nM (TLR7, IL-6 inhibition in mouse blood), shows good selectivity against TLR9 and other TLR family members. |
| PC-73063 |
1V209
TLR7 agonist
|
1V209 is a synthetic small molecule TLR7 specific ligand and agonist. |
| PC-72052 |
CU-115
TLR8 inhibitor
|
CU-115 is a novel potent, selective TLR8 antagonist (inhibitor) with IC50 of 1.4 uM, shows no significant inhibitory effect on TLR7 (IC50>50 uM). |
| PC-72050 |
SM360320
TLR7 agonist
|
SM360320 (CL-087, 1V136) is a potent, orally active and selective TLR7 agonist (ligand). |
| PC-72049 |
M5049
TLR7/8 inhibitor
|
M5049 (Enpatoran, M-5049) is a novel potent, selective TLR7/8 inhibitor with IC50 of 11.1/24.1 nM in HEK NF-kB-luciferase reporter cells assay, repectively |
| PC-38135 |
CU-CPT22
TLR1/TLR2 inhibitor
|
CU-CPT22 is a specific small-molecule inhibitor of the TLR1/TLR2 complex with IC50 of 0.58 uM (NO production in RAW 264.7 cells). |
| PC-38134 |
MMG-11
TLR2 inhibitor
|
MMG-11 (MMG11) is a potent and selective TLR2 antagonist with pA2 values of 5.73 and 6.15 (TLR2/1), preferentially inhibits TLR2/1 signaling. |
| PC-38100 |
Ezeprogind free base
TLR9 inhibitor
|
Ezeprogind (AZP2006) is a lysotropic molecule with neuroprotective effects, binds to PGRN/PSAP complex with higher affinity (Kd=201 nM) than PSAP (Kd=624 nM), inhibits TLR9 receptors. |
| PC-38099 |
Ezeprogind
TLR9 inhibitor
|
Ezeprogind (AZP2006) is a lysotropic molecule with neuroprotective effects, binds to PGRN/PSAP complex with higher affinity (Kd=201 nM) than PSAP (Kd=624 nM), inhibits TLR9 receptors. |
