| Cat. No. |
Product Name |
Information |
| PC-42472 |
Motesanib diphosphate
VEGFR inhibitor
|
Motesanib diphosphate (AMG706) is a potent, orally bioavailable, multikinase inhibitor inhibitor of VEGFR1/2/3, PDGFR and c-Kit with IC50 of 2-6 nM, 84 nM and 8 nM, respectively. |
| PC-42471 |
Motesanib
VEGFR inhibitor
|
Motesanib (AMG706) is a potent, orally bioavailable, multikinase inhibitor inhibitor of VEGFR1/2/3, PDGFR and c-Kit with IC50 of 2-6 nM, 84 nM and 8 nM, respectively. |
| PC-42824 |
Pazopanib hydrochloride
VEGFR inhibitor
|
Pazopanib (GW786034) hydrochloride is a potent, orally available, pan-VEGFR inhibitor with IC50 of 10, 30, and 47 nM for VEGFR-1, -2, and -3, respectively. |
| PC-42453 |
Pazopanib (GW786034)
VEGFR inhibitor
|
Pazopanib (GW786034) is a potent, orally available, pan-VEGFR inhibitor with IC50 of 10, 30, and 47 nM for VEGFR-1, -2, and -3, respectively. |
| PC-42834 |
Vatalanib dihydrochloride
VEGFR inhibitor
|
Vatalanib (PTK787) dihydrochloride is a potent, orally available class III receptor tyrosine kinases inhibitor with IC50 of <1 uM for VEGFR, Flt-1, KDR and PDGFRβ. |
| PC-42448 |
Vatalanib
VEGFR inhibitor
|
Vatalanib (PTK787) is a potent, orally available class III receptor tyrosine kinases inhibitor with IC50 of <1 uM for VEGFR, Flt-1, KDR and PDGFRβ. |
| PC-45898 |
Nintedanib
VEGFR inhibitor
|
Nintedanib (BIBF-1120) is a potent triple angiokinase (VEGFR/PDGFR/FGFR) inhibitor with IC50 of 5/38/18/104/5 nM for VEGFR-2/FGFR-1/PDGFRα/VEGFR-1/VEGFR-3, respectively. |
| PC-45859 |
Linifanib
VEGFR/PDGFR inhibitor
|
Linifanib (ABT-869) is a potent multi-RTKs inhibitor of members of VEGFR and PDGFR families with IC50 of 4/3/3/14/4/66/190/170 nM for KDR/FLT1/CSF1R/KIT/FLT3/PDGFRβ/FLT4/Tie2, respectively. |
| PC-42530 |
Regorafenib
VEGFR inhibitor
|
Regorafenib (BAY 73-4506) is a potent multikinase inhibitor that potently inhibits endothelial cell kinases in biochemical and cellular kinase phosphorylation assays with nanomolar range (IC50=3-200 nM). |
| PC-42557 |
Semaxinib (SU5416)
VEGFR2 inhibitor
|
Semaxinib (SU5416) is a potent and specific VEGFR2 (KDR/Flk-1) inhibitor with IC50 of 1.04 uM. |
| PC-42498 |
Vandetanib hydrochloride
VEGFR2 inhibitor
|
Vandetanib hydrochloride is a potent and selective VEGFR2 (KDR) inhibitor with IC50 of 40 nM. |
| PC-42496 |
Vandetanib
VEGFR2 inhibitor
|
Vandetanib (ZD6474) is a potent and selective VEGFR2 (KDR) inhibitor with IC50 of 40 nM. |
