| Cat. No. |
Product Name |
Information |
| PC-73213 |
CGP 52432
GABAB antagonist
|
CGP 52432 is a potent, selective GABAB receptor antagonist with IC50 of 85 nM. |
| PC-62759 |
CPP-115
|
CPP-115 is an orally available, small molecule, next-generation GABA aminotransferase (GABA-AT) inhibitor with Ki of 31 uM, without other GABAergic or off-target activities. |
| PC-62625 |
PWZ-029
|
PWZ-029 is a potent, subtype-selective partial inverse agonist of α5 GABAA receptors with Ki of 30 nM, demonstrates memory enhancing effects in vivo. |
| PC-62099 |
DCBS152A
|
DCBS152A is a potent, functionally selectiver negative modulator of GABAA receptor at the modulatory PQ site in some receptor isoforms.. |
| PC-62091 |
MK-0343
|
MK-0343 (MRK-409) is a potent, α2/3 subtype selective, partial GABAA receptor agonist, shows greater agonist efficacy at the α3 over α1 subtypes. |
| PC-45592 |
Indiplon
|
A potent GABAA receptor positive allosteric modulator that acts at the benzodiazepine site (Ki values are 1.2 and 1.7 nM in rat frontal cortex and cerebellum respectively). |
| PC-42225 |
U-93631
|
A potent GABAA receptor antagonist that binds the picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. |
| PC-42115 |
DMCM hydrochloride
|
A potent benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity. |
| PC-45628 |
Lorediplon
|
A partial positive allosteric GABAA receptor modulator. |
| PC-45152 |
Acamprosate calcium
|
A GABA receptor agonist and modulator of glutamatergic systems. |
| PC-45172 |
(R)-Baclofen hydrochloride
|
A derivative of the neurotransmitter GABA that acts as a GABAB receptor agonist. |
| PC-42068 |
Pipequaline
|
A clinically-effective anxiolytic that acts as a non-selective partial agonist of benzodiazepine receptor. |
