| Cat. No. |
Product Name |
Information |
| PC-45171 |
(R)-Baclofen
GABAB agonist, VDCC inhibitor
|
(R)-Baclofen (STX-209, Arbaclofen) derivative of the neurotransmitter GABA that acts as a GABAB receptor agonist. |
| PC-28175 |
Stiripentol
GABAA PAM, LDH inhibitor
|
Stiripentol (BCX2600) is an antiepileptic drug that acts directly on GABA(A) receptor as a positive allosteric modulator, also is an lactate dehydrogenase (LDH) inhibitor, inhibits lactate production and decreases glioblastoma invasion and growth. |
| PC-26748 |
α5IA
α5 GABAA receptor inverse agonist
|
α5IA (alpha5IA, L-822179) is a selective inverse agonist selective for α5 subunit-containing GABAA receptors, enhances cognition. |
| PC-26582 |
YX84
GABA A receptor PAM
|
YX84 is a slow-onset, potent positive allosteric modulator (PAM) of GABA A receptor with EC50 of 0.9 uM. |
| PC-25539 |
Isoguvacine hydrochloride
GABAAR agonist
|
Isoguvacine hydrochloride is a potent and selective agonist of the GABA(A) receptor (GABA(A)R). |
| PC-25269 |
QH-ii-66
α5-GABAA receptor agonist
|
QH-ii-66 is a potent, selective agonist of α5-GABAA receptor (GABRA5). |
| PC-25268 |
SR-419
α5-GABAA receptor inhibitor
|
SR-419 is a BBB-impermeable, selective α5-GABAA receptor (GABRA5) inhibitor, shows specific binding to the benzodiazepine site of the GABRA5 receptor, exhibits potent peripheral analgesic effects. |
| PC-25067 |
EL-0052
GABAAR modulator
|
EL-0052 (Lorotomidate, 4-Fluoroetomidate) is a small molecule γ-aminobutyric acid A receptor (GABAAR) modulator, enhances GABAA receptors currents with EC50 of 0.98 uM. |
| PC-24988 |
GABAA receptor agonist CTMB
GABAA receptor agonist
|
CTMB is an allosteric agonist of GABAA receptors, positively modulates GABAA receptors and inhibits voltage-regulated sodium channels (NaVs) to suppress neuronal membrane depolarization. |
| PC-24815 |
Droperidol
CAS 548-73-2
|
Droperidol (Dehydrobenzperidol) is a butyrophenone pamine-2 receptor antagonist, inhibits the activation of GABA(A) and neuronal nicotinic receptors (nAChR) with IC50 of 12.6 nM and 5.8 μM, also specifically inhibits YTHDF2 and prevents associations of YTHDF2 with DDX1 and eIF3F. |
| PC-24505 |
Flumazenil
GABAA antagonist
|
Flumazenil is a central benzodiazepine receptor (IC50=9.91 nM) and competitive GABAA receptor antagonist, reverses the sedative effects of benzodiazepines on the central nervous system. |
| PC-24258 |
ENX-101
⍺2,3,5 GABAA receptor PAM
|
ENX-101 is a α2,α3,α5-selective γ-aminobutyric acid type A (GABAA) receptor partial positive allosteric modulator (PAM), deuterated analog of L-838,417. |
