| Cat. No. |
Product Name |
Information |
| PC-27540 |
AT-121 hydrochloride
MOP/NOP agonist
|
AT-121 hydrochloride (AT121) is a potent, selective bifunctional nociceptin/orphanin FQ peptide / Mu opioid peptide (NOP/MOP) receptor agonist with Ki of 3.67/16.49 nM, respectively. |
| PC-27539 |
AT-121
MOP/NOP agonist
|
AT-121 (AT121) is a potent, selective bifunctional nociceptin/orphanin FQ peptide / Mu opioid peptide (NOP/MOP) receptor agonist with Ki of 3.67/16.49 nM, respectively. |
| PC-27320 |
BPR1M492
MOR agonist
|
BPR1M492 is a potent, selective, fast-acting μ-opioid receptor (MOR) agonist with EC50 of 4 nM in FLIPR Ca2+ assays, Emax=92.7%. |
| PC-27173 |
nor-Binaltorphimine dihydrochloride
KOR antagonist
|
nor-Binaltorphimine dihydrochloride (Nor-BNI, Norbinaltorphimine) is a potent, selective, long-acting competitive κ-opioid receptor (KOR) antagonist, blocks KOR-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. |
| PC-27172 |
nor-Binaltorphimine
KOR antagonist
|
nor-Binaltorphimine (Nor-BNI, Norbinaltorphimine) is a potent, selective, long-acting competitive κ-opioid receptor (KOR) antagonist, blocks KOR-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. |
| PC-27171 |
CTAP TFA
MOR antagonist
|
CTAP TFA is a potent, highly selective, and BBB-penetrant μ opioid receptor (MOR) antagonist with IC50 of 3.5 nM ,> 1200-fold selectivity over δ opioid receptor ( MOR, IC50=4500 nM) and somatostatin receptors. |
| PC-27170 |
CTAP
MOR antagonist
|
CTAP is a potent, highly selective, and BBB-penetrant μ opioid receptor (MOR) antagonist with IC50 of 3.5 nM ,> 1200-fold selectivity over δ opioid receptor ( MOR, IC50=4500 nM) and somatostatin receptors. |
| PC-27169 |
SLL-022CCP
KOR agonist
|
SLL-022CCP is a potent, selective κ-opioid receptor (KOR) agonist with EC50 of 0.002 nM for inhibiting cAMP production, exhibits high receptor subtype selectivity over μ-opioid receptor (MOR, EC50=1.6 nM) and δ-opioid receptor (DOR, EC50=30.0 nM). |
| PC-26942 |
Salvinorin A
KOR agonist
|
Salvinorin A is a potent, selective and high efficacy kappa-opioid receptor (KOR) agonist with Ki value of 4.3 nM. |
| PC-26682 |
MCOPPB trihydrochloride
NOP receptor agonist
|
MCOPPB trihydrochloride is potent, selective nociceptin/orphanin FQ peptide receptor (NOP receptor) with pKi of 10.07, shows 12-, 270- and >1000-fold selectivity over opioid receptors micro-, kappa-, and delta-receptor, respectively. |
| PC-26573 |
Endomorphin-2
μ-opioid receptor agonist
|
Endomorphin-2 (EM-2, Endomorphin 2) a high affinity, highly selective agonist mu-opioid receptor (muOR, μOR) agonist, displays reasonable affinities for kappa3 binding sites with Ki of 20-30 nM. |
| PC-26572 |
Endomorphin-1
μ-opioid receptor agonist
|
Endomorphin-1 (EM-1, Endomorphin 1) a high affinity, highly selective agonist mu-opioid receptor (muOR, μOR) agonist with Ki of 1.11 nM, displays reasonable affinities for kappa3 binding sites, has antinociceptive properties. |
