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Cat. No. Product Name Information
PC-22777

DAMGO

MOR agonist

DAMGO is a highly affinity, selective peptide agonist of mu-opioid receptor (MOR) with Kd of 3.46 nM.
PC-22776

BPRMU191

MOR modulator

BPRMU191 is a unique mu-opioid receptor (MOR) modulator with EC50 of 2.17 uM in FLIPR Ca2+ assay using CHO-K1/MOR/Gα15 cells, BPRMU191 binds to MOR in the presence of naloxone.
PC-22594

µOR inhibitor 368

δ-opioid receptor NAM

µOR inhibitor 368 (µOR NAM 368, Compound 368) is a potent, negative allosteric modulator (NMA)/inhibitor of µ-opioid receptor (µOR), significantly inhibits met-enkephalin-induced µOR activation of Gi, increases binding of 3H-naloxone with EC50 of 133 nM.
PC-22000

LY2444296

KOR inhibitor

LY2444296 is a potent, selective orally bioavailable, and short-acting kappa opioid receptor (KOPR) antagonist with Ki of 1 nM.
PC-21949

Sunobinop

NOP agonist

Sunobinop is a potent and partial agonist of the nociceptin/orphanin FQ peptide receptor (NOP receptor) with Ki of 3.3 nM, EC50 of 4.03 nM.
PC-21793

LY2817412

NOP antagonist

LY2817412 is a potent, selective andorally active nociceptin/orphanin FQ (NOP) receptor antagonist with Ki of 0.176 nM, Kb of 0.273 nM in functional assay of receptor-mediated G-protein activation using [35S]-GTPγS binding.
PC-21712

PIPE-3297

KOR agonist

PIPE-3297 is a fully efficacious and selective kappa opioid receptor (KOR) agonist with functional GTPγS EC50 of 1.1 nM, Emax=91%, does not elicit β-arrestin-2 recruitment functional response.
PC-21574

ZYKR1

KOR agonist

ZYKR1 is a potent, and peripherally restricted kappa opioid receptor (KOR)-selective agonist with EC50 of 0.061 nM in cAMP assays, highly selective over the mu and delta opioid receptors (EC50>10 μM).
PC-20520

LY255582

Pan-opioid antagonist

LY255582 is a potent, pan-opioid antagonist with Ki value of for 0.4 nM, 5.2 nM and 2.0 nMmu, delta, and kappa receptors, respectively, decreases short- and long-term food intake in rats.
PC-20510

AT-076

Pan opioid antagonist

AT-076 (AT076) is the first potent small-molecule opioid pan antagonist with receptor binding Ki values of 1.75, 1.14, 1.67 and 19.6 nM for NOP, KOP, MOP, and DOP, respectively.
PC-49745

RM1490

MOR agonist

RM1490 (RM 1490) is a potent, brain-penetrant µ opioid receptor (MOR) agonist with EC50 of 3.4 and 4.4 nM in GTPγS and cAMP assays, respectively.
PC-47497

D-Ala2, D-Leu5-Enkephalin

An angiotensin II analog that is an agonist of AT1 angiotensin receptor..

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