| Cat. No. |
Product Name |
Information |
| PC-21712 |
PIPE-3297
KOR agonist
|
PIPE-3297 is a fully efficacious and selective kappa opioid receptor (KOR) agonist with functional GTPγS EC50 of 1.1 nM, Emax=91%, does not elicit β-arrestin-2 recruitment functional response. |
| PC-21574 |
ZYKR1
KOR agonist
|
ZYKR1 is a potent, and peripherally restricted kappa opioid receptor (KOR)-selective agonist with EC50 of 0.061 nM in cAMP assays, highly selective over the mu and delta opioid receptors (EC50>10 μM). |
| PC-20520 |
LY255582
Pan-opioid antagonist
|
LY255582 is a potent, pan-opioid antagonist with Ki value of for 0.4 nM, 5.2 nM and 2.0 nMmu, delta, and kappa receptors, respectively, decreases short- and long-term food intake in rats. |
| PC-20510 |
AT-076
Pan opioid antagonist
|
AT-076 (AT076) is the first potent small-molecule opioid pan antagonist with receptor binding Ki values of 1.75, 1.14, 1.67 and 19.6 nM for NOP, KOP, MOP, and DOP, respectively. |
| PC-49745 |
RM1490
MOR agonist
|
RM1490 (RM 1490) is a potent, brain-penetrant µ opioid receptor (MOR) agonist with EC50 of 3.4 and 4.4 nM in GTPγS and cAMP assays, respectively. |
| PC-49552 |
DPI-287
DOP agonist
|
DPI-287 is a small-molecule agonist of the δ-opioid receptor (DOP) with Ki vaule of 0.39 nM, shows 10-fold selectivity for DOP over MOP (Ki=3.17 nM). |
| PC-47027 |
AT-403
NOP agonist
|
AT-403 is a potent, selective agonist of nociceptin opioid peptide (NOP) receptor, decreases blood pressure and produce aquaresis in conscious rodents. |
| PC-47026 |
AT-039
NOP agonist
|
AT-039 is a potent, selective agonist of nociceptin opioid peptide (NOP) receptor, AT-039 is useful for treatment of hypertension and/or volume overload/hyponatraemic states. |
| PC-38589 |
BPR1M97
MOP/NOP agonist
|
BPR1M97 is a dual-acting mu-opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with Ki values of 1.8 and 4.2 nM, respectively. |
| PC-38532 |
BMS 986188
δ-opioid PAM
|
BMS 986188 is a potent, selective positive allosteric modulator of δ-opioid receptor with EC50 of 0.05 uM in β-arrestin recruitment assays, no significant acitivity against μ-opioid receptors. |
| PC-73447 |
Tegileridine
MOR agonist
|
Tegileridine is a selective mu opioid receptor (MOR) agonist with analgesic activity. |
| PC-73442 |
Riminkefon
Opioid Receptor agonist
|
Riminkefon is a potent kappa opioid receptor agonist with analgesic activity. |
