| Cat. No. |
Product Name |
Information |
| PC-22476 |
TRK inhibitor 19k
TRK inhibitor
|
TRK inhibitor 19k is a potent, selective pan tropomyosin receptor kinase (pan-TRK) inhibitor with IC50 of 23/25/21 nM for TRKA/B/C, respectively. |
| PC-22385 |
LM22B-10
TrkB/TrkC agonist
|
LM22B-10 is a small moelcule agonist neurotrophin (NT) receptor TrkB and TrkC, selectively binds to and activates TrkB as well as TrkC, shows neurotrophic activitie. |
| PC-21241 |
PTX-BD10-2
TrkB/C agonist
|
PTX-BD10-2 (BD10-2) is a selective, brain-penetrant small molecule TrkB/C receptor partial agonist, shows survival-promoting activity. |
| PC-20760 |
TrkB agonist R13
TrkB agonist
|
TrkB agonist R13 is a small molecular TrkB receptor agonist prodrug, inhibits asparagine endopeptidase (AEP) and promotes bone formation. |
| PC-43266 |
LOXO-101 sulfate
|
LOXO-101 (ARRY-470, Larotrectinib) is potent, selective pan-TRK inhibitor with cellular IC50 of 2-20 nM against TRKA, TRKB, and TRKC kinases. |
| PC-70344 |
Deoxygedunin
|
A naturally occurring tetranortriterpenoid that has been found to act as a potent, selective, small-molecule agonist of TrkB with Kd of 1.4 uM. |
| PC-60902 |
LOXO-195 RS-isomer
|
The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.. |
