| Cat. No. |
Product Name |
Information |
| PC-42147 |
Odanacatib
Cathepsin K inhibitor
|
Odanacatib (MK-0822) is a potent, selective, reversible and orally active cathepsin K inhibitor with IC50 of 0.2 nM. |
| PC-45577 |
MG-101
Cysteine proteases inhibitor
|
MG-101 (ALLN) is a potent inhibitor of cysteine proteases including calpain I (Ki= 190 nM), calpain II (Ki= 220 nM), cathepsin B (Ki= 150 nM) and cathepsin L (Ki= 500 pM).
|
| PC-22251 |
JNJ-10311795
Cathepsin G inhibitor
|
JNJ-10311795 is a potent dual inhibitor of neutrophil cathepsin G (Ki=38 nM) and mast cell chymase (Ki=2.3 nM), exhibits noteworthy anti-inflammatory activity in rats for glycogen-induced peritonitis and LPS-induced airway inflammation. |
| PC-22250 |
Cathepsin G inhibitor KPA
Cathepsin G inhibitor
|
Cathepsin G inhibitor KPA is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (CatG) with IC50 of 53 nM. |
| PC-22165 |
ASP1617
Cathepsin S inhibitor
|
ASP1617 (ASP-1617) is a potent, highly specific and orally active cathepsin S (CatS) inhibitor with IC50 of 4.6 nM and 0.39 nM for human and mouse CatS, respectively. |
| PC-22164 |
RO5461111
Cathepsin S inhibitor
|
RO5461111 is a potent, highly specific and orally active cathepsin S (CatS) inhibitor with IC50 of 0.4 nM and 0.5 nM for human and mouse CatS respectively. |
| PC-21937 |
Balicatib
Cathepsin K inhibitor
|
Balicatib (AAE581) is a potent, selective and orally active and selective cathepsin K inhibitor with IC50 of 22 nM. |
| PC-21936 |
CA-074
Cathepsin B inhibitor
|
CA-074 is a potent, specific and cell-permeable inhibitor of cathepsin B with Ki of 2-5 nM. |
| PC-21763 |
VBY-825
Cathepsin S inhibitor
|
VBY-825 is an reversible cathepsin inhibitor of cathepsins B, L, S and V.with Ki values of 130/250/250/330/2.3/4.7 nM (cathepsin S/L/ZV/Bhumanized-rabbit cathepsin K/cathepsin F). |
| PC-20410 |
Z-Tyr-Ala-CHN2
Cathepsin L inhibitor
|
Z-Tyr-Ala-CHN2 is a potent cathepsin L inhibitor with EC50 of <50 nM, has broad-spectrum coronavirus antiviral activity. |
| PC-20203 |
Dutacatib
Cathepsin K inhibitor
|
Dutacatib (AFG495) is potent, selective and non-covalent cathepsin K inhibitor with IC50 of 3-6 nM (human CatK), shows excellent selectivity profile versus human cathepsins L and S. |
| PC-38582 |
SID 26681509
Cathepsin L inhibitor
|
SID 26681509 is a potent, selective inhibitor of lysosome hydrolase cathepsin L with IC50 of 56 nM, displays no inhibitory activity at cathepsin G. |
