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Cat. No. Product Name Information
PC-38256

ALKBH5 inhibitor 6

ALKBH5 inhibitor

ALKBH5 inhibitor 6 is a small molecule inhibitor of RNA 6-N-methyladenosine (m6A) demethylase ALKBH5, inhibits ALKBH5 RNA m6A demethylation activity with IC50 of 1.79 uM.
PC-38255

ALKBH5 inhibitor 3

ALKBH5 inhibitor

ALKBH5 inhibitor 3 is a small molecule inhibitor of RNA 6-N-methyladenosine (m6A) demethylase ALKBH5, inhibits ALKBH5 RNA m6A demethylation activity with IC50 of 0.84 uM.
PC-38254

MV1035

ALKBH5 inhibitor

MV1035 (MV-1035) is a novel small molecule that reduce U87 GBM cells migration and invasiveness, targeting m6A demethylase ALKBH5, also inhibits ALKBH2.
PC-38127

INCB059872

LSD1 inhibitor

INCB059872 (INCB-059872, INCB 59872) is a potent, selective, and orally active lysine-specific demethylase 1 (LSD1) inhibitor.
PC-36169

FB23-2

FTO inhibitor

FB23-2 is a potent, selective inhibitor of the mRNA N 6-methyladenosine (m 6A) demethylase FTO, directly bind to FTO, inhibits FTO demethylation of m6 A in RNA in vitro with IC50 of 2.6 uM.
PC-35903

T-448 free base

LSD1 inhibitor

T-448 free base (T448) is a specific inhibitor of LSD1 enzyme activity, enhances H3K4 methylation in primary cultured rat neurons but has little impact on LSD1-GFI1B complex in human TF-1a erythroblasts.
PC-35902

T-448

LSD1 inhibitor

T-448 (T448) is a specific inhibitor of LSD1 enzyme activity, enhances H3K4 methylation in primary cultured rat neurons but has little impact on LSD1-GFI1B complex in human TF-1a erythroblasts.
PC-35801

KDM5A covalent inhibitor N73

KDM5A inhibitor

KDM5A covalent inhibitor N73 is the the isopropyl ester derivative of N71, an irreversible KDM5A inhibitor (IC50=0.22 uM) that covalently interacts with Cys481, >20-fold selectivity over KDM4A..
PC-35800

KDM5A covalent inhibitor N71

KDM5A inhibitor

KDM5A covalent inhibitor N71 is an irreversible KDM5A inhibitor (IC50=0.22 uM) that covalently interacts with Cys481, >20-fold selectivity over KDM4A..
PC-35794

LSD1 inhibitor 24

LSD1 inhibitor

LSD1 inhibitor 24 is a novel potent, selective lysine-specific demethylase 1 (LSD1) inhibitor with IC50 of 1 nM, induces CD11b expression in THP-1 cells with EC50 of 8 nM.
PC-35471

Vafidemstat

LSD1 inhibitor

Vafidemstat (ORY-2001, ORY2001) is a potent, selective, brain penetrant dual lysine-specific histone demethylase (LSD1, KDM1A)/MAO-B inhibitor with IC50 of 105 nM (KDM1A) and 58 nM (MAO-B).
PC-35458

ORY-1001 dihydrochloride

LSD1 inhibitor

ORY-1001 dihydrochloride (RG-6016, Ladademstat) is a highly potent, selective inhibitor of lysine-specific demethylase KDM1A (LSD1) with IC50 of 18 nM, displays high selectivity for KDM1A over other FAD-containing monoamine oxidases.

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