| Cat. No. |
Product Name |
Information |
| PC-62293 |
GS-5801
KDM5 inhibitor
|
KDM5-C70 (GS-5801) is a cell-permeable derivative of KDM5-C49 (GS-080), potent, selective and cell permeable KDM5 inhibitor with IC50 of 0.3, 0.3 and 0.58 uM for KDM5A, B and C, respectively. |
| PC-62292 |
GSK-467
KDM5 inhibitor
|
GSK-467 is a potent, selective KDM5 inhibitor with Ki of 10 nM, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other JmJ family members. |
| PC-61956 |
NCD-25
LSD1 inhibitor
|
NCD-25 is a novel potent, selective LSD1 inhibitor with IC50 of 0.48 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO.. |
| PC-61955 |
NCD-38
LSD1 inhibitor
|
NCD-38 is a novel potent, selective LSD1 inhibitor with IC50 of 0.59 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO (IC50>100 uM). |
| PC-61816 |
E67-2
KDM7A inhibitor
|
E67-2 is a potent and selective inhibitor of H3K9 Jumonji demethylase KIAA1718 (KDM7A) with IC50 of 3.4 uM. |
| PC-61815 |
KDM2A/7A inhibitor 1
KDM2A/7A inhibitor
|
KDM2A/7A inhibitor 1 is a potent, highly selective and cell-active inhibitor of KDM2A/7A with IC50 of 0.16 and 0.19 uM, respectively. |
| PC-61746 |
OG-L002
LSD1 inhibitor
|
OG-L002 is a novel selective LSD1 inhibitor with IC50 of 20 nM. |
| PC-61745 |
GSK690
LSD1 inhibitor
|
GSK690 is a reversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1, KDM1A) with IC50 of 37 nM, binding Kd value of 9 nM. |
| PC-61739 |
QC6352
KDM4 inhibitor
|
QC-6352 is a potent and selective KDM4 family inhibitor with IC50 of 104, 56, 35, and 104 nM for KDM4A, KDM4B, KDM4C, and KDM4D, respectively. |
| PC-61732 |
LSD1-IN-32
LSD1 inhibitor
|
LSD1-IN-32 is a potent, reversible lysine specific demethylase 1 (LSD1) inhibitor with biochemical IC50 of 83 nM, Kd of 32 nM, cell EC50 of 0.67 uM. |
| PC-61645 |
S-2101
LSD1 inhibitor
|
S-2101 is a potent lysine-specific demethylase 1 (LSD1) inhibitor with Ki of 0.61 uM. |
| PC-61644 |
LSD1 inhibitor-1
LSD1 inhibitor
|
LSD1 inhibitor-1 is a bisguanidine polyamine analogue that exhibits noncompetitive and specific LSD1 inhibition, with 14.1% remaining LSD1 activity at 10 uM in vitro. |
