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Cat. No. Product Name Information
PC-22089

ALKBH5 inhibitor TD19

ALKBH5 inhibitor

ALKBH5 inhibitor TD19 is a specific, covalent inhibitor of RNA demethylase ALKBH5, inhibits ALKBH5-induced demethylation with IC50 of 1.5-3 uM.
PC-21840

P3FI-90

KDM3B inhibitor

P3FI-90 is a specific small molecule inhibitor of KDM3B with SPR KD of 7.68 uM, inhibits PAX3-FOXO1 activity and blocks PAX3-FOXO1 downstream target gene expression.
PC-21085

JMJD5 inhibitor 19j

JMJD5 inhibitor

JMJD5 inhibitor 19j is a potent selective small molecule inhibitor of 2OG-dependent oxygenase JMJD5 (KDM8), shows high selectivity over other human 2OG oxygenases.
PC-20355

KDM5B inhibitor 27ab

KDM5B inhibitor

KDM5B inhibitor 27ab is a potent inhibitor of histone lysine specific demethylase 5B (KDM5B/JARID1B) with IC50 of 24.4 nM.
PC-20354

KDM5A inhibitor compound 1

KDM5A inhibitor

KDM5A inhibitor compound 1 (ZINC33576) is a potent, selective KDM5A (JARID1A) inhibitor with IC50 of 23.8 nM.
PC-20353

CBA-1

KDM3A inhibitor

CBA-1 is a small molecule inhibitor of Wnt signaling, specifically targets Jumonji (JmjC) domain-containing demethylase KDM3A with IC50 of 3.9 uM.
PC-20352

EPZ020809

KDM4C inhibitor

EPZ020809 is a potent, specific KDM4C inhibitor with Ki of 31 nM, binds KDM4C in a 2-OG-competitive fashion.
PC-20255

Bomedemstat

LSD1 inhibitor

Bomedemstat (IMG-7289) is a potent, selective, irreversible and orally active LSD1 (KDM1A) inhibitor, increases H3K4 and H3K9 methylation.
PC-49244

iJMJD6

JMJD6 inhibitor

iJMJD6 is a potent, specific small-molecule JMJD6 inhibitor that specifically binds to JMJD6 (ITC Kd=3.83 uM) and competes with α-KG and the substrate for binding, inhibits the demethylase activity of JMJD6 with IC50 of 149.6 nM.
PC-49236

FTO-43

FTO inhibitor

FTO-43 (FTO-43 N) is a potent, selective inhibitor of the m6A demethylase fat mass- and obesity-associated protein (FTO) with IC50 of 1.0 uM, no significant acitivity against the homologous m6A RNA demethylase ALKBH5 (IC50>40 uM).
PC-38672

Pulrodemstat benzenesulfonat

LSD1 inhibitor

Pulrodemstat (CC-90011) is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with biochemical IC50 of 0.3 nM.
PC-38671

Pulrodemstat

LSD1 inhibitor

Pulrodemstat (CC-90011) is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with biochemical IC50 of 0.3 nM.

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