Cat. No. |
Product Name |
Information |
PC-21684 |
iPHF8
PHF8 inhibitor
|
iPHF8 (inhibitor of PHF8) is a specific inhibitor of protein demethylase PHF8 with IC50 of 2.01 uM in Succinate-Glo JmjC demethylase assays, and SPR KD value of 240 nM. |
PC-21211 |
GSK-J4
KDM6A/6B inhibitor
|
GSK-J4 is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 μM, respectively, GSK-J4 s a cell permeable prodrug of GSK-J1. |
PC-20876 |
ZY0511
LSD1 inhibitor
|
ZY0511 is a highly selective and potent inhibitor of lysine‐specific histone demethylase 1 (LSD1) with IC50 of 1.7 nM and SPR Kd of 2.42 nM. |
PC-20519 |
TAK-418
LSD1 (KDM1A) inhibitor
|
TAK-418 (TAK418) is a potent, specific inhibitor of LSD1 (KDM1A) enzyme activity with IC50 of 2.9 nM. |