Histone Demethylase compound (inhibitors, agonists)-ProbeChem.com

Request The Product List ofHistone Demethylase Histone Demethylase

Cat. No.	Product Name	Information
PC-21987	PBIT KDM5 inhibitor	PBIT is a specific small molecule inhibitor of JARID1 family of histone lysine demethylases (KDM5) with IC50 of 3 uM for JARID1B (KDM5B or PLU1), inhibits H3K4me3 demethylation in vitro and in vivo.
PC-21915	ALKBH1 inhibitor 13h ALKBH1 inhibitor	ALKBH1 inhibit 13h is a potent, isoform selective, and cell-active DNA 6mA demethylase ALKBH1 inhibitor with 26 nM and 1.39 uM in FP and enzyme activity assay, respectively.
PC-21875	WS-384 LSD1 inhibitor	WS-384 is a specific, small-molecule inhibitor dually targeting LSD1 (IC50=338.8 nM) and the DCN1-UBC12 interaction (IC50=14.8 uM).
PC-21777	JMJD1C inhibitor 193D7 JMJD1C inhibitor	193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells.
PC-21684	iPHF8 PHF8 inhibitor	iPHF8 (inhibitor of PHF8) is a specific inhibitor of protein demethylase PHF8 with IC50 of 2.01 uM in Succinate-Glo JmjC demethylase assays, and SPR KD value of 240 nM.
PC-20876	ZY0511 LSD1 inhibitor	ZY0511 is a highly selective and potent inhibitor of lysine‐specific histone demethylase 1 (LSD1) with IC50 of 1.7 nM and SPR Kd of 2.42 nM.
PC-20519	TAK-418 LSD1 (KDM1A) inhibitor	TAK-418 (TAK418) is a potent, specific inhibitor of LSD1 (KDM1A) enzyme activity with IC50 of 2.9 nM.

PREV 1 2 3 4 5 6 7 89NEXT