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Cat. No. Product Name Information
PC-61643

RN-1 dihydrochloride

LSD1 inhibitor

RN-1 dihydrochloride is a potent, irreversible, brain-penetrant inhibitor of LSD1 with IC50 of 70 nM.
PC-61398

Seclidemstat

LSD1 inhibitor

Seclidemstat (SP-2577, SP2577) is a potent, selecftive and reversible LSD1 inhibitor with IC50 of 13 nM in biochemical assays.
PC-70332

SD-70

KDM4C inhibitor

SD-70 is a small molecule tumor translocation inhibitor that inhibits the prostate cancer cell transcriptional program, in part by inhibition of the demethylase KDM4C (IC50=30 uM).
PC-60265

T-3775440 hydrochloride

LSD1 inhibitor

T-3775440 hydrochloride (T 3775440, T3775440) is a potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM.
PC-60264

T-3775440

LSD1 inhibitor

T-3775440 (T 3775440, T3775440) is a novel potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM.
PC-60020

KDOAM-25

KDM5 inhibitor

KDOAM-25 (KDM5 inhibitor KDOAM 25) is a potent, selective KDM5 sub-family(JARID1) inhibitor with biochemical IC50 of 71/19/69/69 nM for KDM5A/B/C/D, respectively.
PC-45657

DDP-38003 dihydrochloride

LSD1 inhibitor

DDP-38003 dihydrochloride is a potent, selective and orally available inhibitor of histone lysine-specific demethylase 1A (KDM1A/LSD1) with IC50 of 84 nM.
PC-42028

KDM5A-IN-1

KDM5A-IN-1 is a potent, orally bioavailable histone lysine demethylases 5 (KDM5) inhibitor with IC50 of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively.
PC-42148

CPI-455

KDM5 inhibitor

CPI-455 is a potent, specific histone demethylase pan-KDM5 inhibitor with biochemical IC50 of 10, 3 and 14 nM for KDM5A, KDM5B and KDM5C, respectively.
PC-45495

GSK-2879552

LSD1 inhibitor

GSK-2879552 is a potent, selective irreversible inhibitor of LSD1 with Ki app of 1.7 uM.
PC-42149

KDM5-IN-48

KDM5 inhibitor

KDM5-IN-48 is a potent, selective and orally bioavailable KDM5 inhibitor with biochemical IC50 of 15.1, 4.7 and 65.5 nM for KDM5A, KDM5B and KDM5C, respectively.
PC-42195

D-alpha-Hydroxyglutaric acid disodium

Dioxygenase inhibitor

D-alpha-Hydroxyglutaric acid disodium (D-2-HG, D-2-hydroxyglutarate) is a competitive inhibitor of multiple α-KG-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases.

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