| Cat. No. |
Product Name |
Information |
| PC-61816 |
E67-2
KDM7A inhibitor
|
E67-2 is a potent and selective inhibitor of H3K9 Jumonji demethylase KIAA1718 (KDM7A) with IC50 of 3.4 uM. |
| PC-61815 |
KDM2A/7A inhibitor 1
KDM2A/7A inhibitor
|
KDM2A/7A inhibitor 1 is a potent, highly selective and cell-active inhibitor of KDM2A/7A with IC50 of 0.16 and 0.19 uM, respectively. |
| PC-61746 |
OG-L002
LSD1 inhibitor
|
OG-L002 is a novel selective LSD1 inhibitor with IC50 of 20 nM. |
| PC-61745 |
GSK690
LSD1 inhibitor
|
GSK690 is a reversible, mechanism based inhibitor of lysine specific demethylase 1 (LSD1, KDM1A) with IC50 of 37 nM, binding Kd value of 9 nM. |
| PC-61739 |
QC6352
KDM4 inhibitor
|
QC-6352 is a potent and selective KDM4 family inhibitor with IC50 of 104, 56, 35, and 104 nM for KDM4A, KDM4B, KDM4C, and KDM4D, respectively. |
| PC-61732 |
LSD1-IN-32
LSD1 inhibitor
|
LSD1-IN-32 is a potent, reversible lysine specific demethylase 1 (LSD1) inhibitor with biochemical IC50 of 83 nM, Kd of 32 nM, cell EC50 of 0.67 uM. |
| PC-61645 |
S-2101
LSD1 inhibitor
|
S-2101 is a potent lysine-specific demethylase 1 (LSD1) inhibitor with Ki of 0.61 uM. |
| PC-61644 |
LSD1 inhibitor-1
LSD1 inhibitor
|
LSD1 inhibitor-1 is a bisguanidine polyamine analogue that exhibits noncompetitive and specific LSD1 inhibition, with 14.1% remaining LSD1 activity at 10 uM in vitro. |
| PC-61643 |
RN-1 dihydrochloride
LSD1 inhibitor
|
RN-1 dihydrochloride is a potent, irreversible, brain-penetrant inhibitor of LSD1 with IC50 of 70 nM. |
| PC-61398 |
Seclidemstat
LSD1 inhibitor
|
Seclidemstat (SP-2577, SP2577) is a potent, selecftive and reversible LSD1 inhibitor with IC50 of 13 nM in biochemical assays. |
| PC-70332 |
SD-70
KDM4C inhibitor
|
SD-70 is a small molecule tumor translocation inhibitor that inhibits the prostate cancer cell transcriptional program, in part by inhibition of the demethylase KDM4C (IC50=30 uM). |
| PC-60265 |
T-3775440 hydrochloride
LSD1 inhibitor
|
T-3775440 hydrochloride (T 3775440, T3775440) is a potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM. |
