Histone Demethylase compound (inhibitors, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-22360	KDM4/5 inhibitor 19a KDM4/5 inhibitor	KDM4/5 inhibitor 19a is a potent, cell penetrant, dual KDM4/5-subfamily inhibitor with Ki values of 4 nM/7 nM for KDM4A/KDM5B, respectively.
PC-22359	N19-0881 KDM5B inhibitor	KDM5-N19 (N19-0881) is a potent, selective, αKG-competitive KDM5B inhibitor with IC50 of 2 nM.
PC-22357	2,4-PDCA 2OG oxygenase inhibitor	2,4-PDCA (2,4 pyridine dicarboxylic acid) is a broad-spectrum inhibitor of 2OG oxygenases, including JmjC domain-containing family of histone demethylases (JHDMs), shows acceptable KDM5B inhibition in vitro, with an IC50 value of 3 uM.
PC-21777	JMJD1C inhibitor 193D7 JMJD1C inhibitor	193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells.

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