| Cat. No. |
Product Name |
Information |
| PC-26512 |
XL784
SVMP inhibitor
|
XL784 is a potent limited-spectrum MMP inhibitor with IC50 of 0.81, 120, 10.8, 18, 0.56 nM for MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, also inhibits snake venom metalloproteinase (SVMP) toxin. |
| PC-26511 |
DC-174
SVMP inhibitor
|
DC-174 is a potent broad-spectrum snake venom metalloproteinases (SVMPs) inhibitor with enzymetic EC50 of 4.7 nM for ERO (E. romani) SVMP. |
| PC-25877 |
JG26
ADAM17 inhibitor
|
JG26 is a potent, selective ADAM17 inhibitor with IC50 of IC50 of 1.9 nM, weakly inhibits ADAM-10 and MMP-2 (IC50=150 and 240 nM), does not inhibit MMP-1/9/14. |
| PC-25431 |
ADAM17 inhibitor 2155-17
ADAM17 inhibitor
|
ADAM17 inhibitor 2155-17 is a specific small molecule ADAM17 inhibitor with IC50 of 4.3 uM, with no activity against MMP2, MMP8, MMP9 ,MMP14, and ADAM10 (IC50>100 uM). |
| PC-24146 |
Linvemastat
MMP-12 inhibitor
|
Linvemastat is a potent, selective matrix metalloproteinase MMP-12 inhibitor. |
| PC-23272 |
GHK-Cu
Wound repair activator
|
GHK-Cu (glycyl-L-histidyl-L-lysine Cu2+ tripeptide) is a growth factor for differentiated cells and a potential activator of wound repair, increases extracellular matrix accumulation, increases MMP-2 levels in conditioned media of cultured fibroblasts.| |
| PC-23169 |
Doxycycline hydrochloride
NS2B-NS3 inhibitor
|
Doxycycline hydrochloride is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor, also is the orthoflaviviral NS2B-NS3 protease inhibitor, shows antiviral and anti-cancer cell proliferation activities. |
| PC-23168 |
Doxycycline
NS2B-NS3 inhibitor
|
Doxycycline is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor, also is the orthoflaviviral NS2B-NS3 protease inhibitor, shows antiviral and anti-cancer cell proliferation activities. |
| PC-23034 |
ADAMTS-IN-1
ADAMTS-4/ADAMTS-5 inhibitor
|
ADAMTS-IN-1 is a potent dual inhibitor of ADAMTS-5 and ADAMTS-4 with IC50s of 8 and 12 nM, respectively, example 37-2 in Patent WO2021158626 A. |
| PC-23033 |
ADAMTS-5 inhibitor 12
ADAMTS-5 Inhibitor
|
ADAMTS-5 inhibitor 12 is a potent selective ADAMTS-5 (aggrecanase-2) inhibitor with IC50 of 1.1 uM, >40-fold functional selectivity over ADAMTS-4 (aggrecanase-1). |
| PC-22949 |
ADAMTS7 inhibitor 3a
ADAMTS7 inhibitor
|
ADAMTS7 inhibitor 3a is a potent, selective ADAMTS7 inhibitor with Ki of 9 nM, 12-fold selective over ADAMTS5 (Ki=110 nM). |
| PC-22948 |
EDV33
ADAMTSs inhibitor
|
EDV33 is a potent, non-selective inhibitor of ADAMTSs with Ki app value of 68, 31, 6.5, 4.3 and 4.0 nM for ADAMTS-7, ADAMTS-4, ADAMTS-5, ADAM-17 and MMP-2 respectively. |
