| Cat. No. |
Product Name |
Information |
| PC-22480 |
PD166793
MMP inhibitor
|
PD166793 (PD-166793 ) is a selective, orally active broad spectrum inhibitor of MMPs with IC50 of 4, 7, and 8 nM for MMP-2, MMP-3 and MMP-13, inhibits MMP-1, MMP-7 and MMP-9 with IC50 of 6-8 uM. |
| PC-21754 |
ADAMTS7 inhibitor 50
ADAMTS7 inhibitor
|
ADAMTS7 inhibitor 50 is a potent selective ADAMTS7 inhibitor with IC50 of 2 nM, 20-fold selective over ADAMTS12 and highly selective over a range of metalloproteases. |
| PC-21674 |
TP0628103
MMP-7 inhibitor
|
TP0628103 is a highly potent, selective matrix metalloproteinase-7 (MMP-7) inhibitor with IC50 of 0.17 nM and 4.1 nM for human and mouse MMP-7, respectively. |
| PC-21092 |
TAPI-1
ADAM17 inhibitor
|
TAPI-1 is a small molecule inhibitor of TNFalpha converting enzyme (TACE, ADAM7), blocks the shedding of several cell surface proteins. |
| PC-21091 |
TAPI-0
ADAM17 inhibitor
|
TAPI-0 is a potent, selective inhibitor of TNFalpha converting enzyme (TACE, ADAM7) with IC50 of 100 nM. |
| PC-20621 |
CID 3117694
ADAM10 inhibitor
|
CID 3117694 is a selective, non-competitive inhibitor of ADAM10 with IC50 of 1.1 uM, does not inhibit ADAM17. |
| PC-20588 |
ARP100
MMP2 inhibitor
|
ARP100 (ARP-100) is a potent, selective gelatinase A (MMP-2) inhibitor with IC50 of 12 nM, weakly inhibits MMP-9 (IC50=200 nM) and >300-fold selectivity over MMP1/3/7. |
| PC-20537 |
MMP-12 inhibitor 9
MMP-12 inhibitor
|
MMP-12 inhibitor 9 is a potent selective MMP-12 inhibitor with IC50 of 177 nM, displays anti-inflammatory activity in vitro and in vivo. |
