| Cat. No. |
Product Name |
Information |
| PC-42904 |
Marimastat
MMP inhibitor
|
Marimastat (BB-2516, TA-2516) is a potent, broad spectrum MMP inhibitor for MMP9/1/2/14/7 with IC50 of 3/5/6/9/13 nM, respectively. |
| PC-28299 |
MMP-13-IN-1
MMP-13 inhibitor
|
MMP-13-IN-1 (Compound 15j) is a highly potent and selective MMP-13 inhibitor with IC50 of 16 nM. |
| PC-28296 |
AZD6605
MMP-13 inhibitor
|
AZD6605 (AZD-6605) is a potent and selective inhibitor of MMP-13 (MMP13) with IC50 of 4.7 nM, 430-fold selective over MMP-14. |
| PC-27371 |
Adamastat
ADAM15 inhibitor
|
Adamastat is a specific small molecule ADAM15 inhibitor, triggers the reduction of bladder cancer cell viability. |
| PC-26813 |
JNJ0966
MMP-9 inhibitor
|
JNJ0966 is a potent, highly selective inhibitor of matrix metalloproteinase-9 (MMP-9) with IC50 of 440 nM in proMMP-9 activation assays. |
| PC-26575 |
UK-383367
BMP1 inhibitor
|
UK-383367 (UK-383,367) is a potent, selective non-peptidic procollagen C-proteinase (PCP, BMP-1) with IC50 of 44 nM, shows no significant activity against a panel of MMPs. |
| PC-26512 |
XL784
SVMP inhibitor
|
XL784 is a potent limited-spectrum MMP inhibitor with IC50 of 0.81, 120, 10.8, 18, 0.56 nM for MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, also inhibits snake venom metalloproteinase (SVMP) toxin. |
| PC-26511 |
DC-174
SVMP inhibitor
|
DC-174 is a potent broad-spectrum snake venom metalloproteinases (SVMPs) inhibitor with enzymetic EC50 of 4.7 nM for ERO (E. romani) SVMP. |
| PC-25877 |
JG26
ADAM17 inhibitor
|
JG26 is a potent, selective ADAM17 inhibitor with IC50 of IC50 of 1.9 nM, weakly inhibits ADAM-10 and MMP-2 (IC50=150 and 240 nM), does not inhibit MMP-1/9/14. |
| PC-25431 |
ADAM17 inhibitor 2155-17
ADAM17 inhibitor
|
ADAM17 inhibitor 2155-17 is a specific small molecule ADAM17 inhibitor with IC50 of 4.3 uM, with no activity against MMP2, MMP8, MMP9 ,MMP14, and ADAM10 (IC50>100 uM). |
| PC-23169 |
Doxycycline hydrochloride
NS2B-NS3 inhibitor
|
Doxycycline hydrochloride is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor, also is the orthoflaviviral NS2B-NS3 protease inhibitor, shows antiviral and anti-cancer cell proliferation activities. |
| PC-23168 |
Doxycycline
NS2B-NS3 inhibitor
|
Doxycycline is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor, also is the orthoflaviviral NS2B-NS3 protease inhibitor, shows antiviral and anti-cancer cell proliferation activities. |
