| Cat. No. |
Product Name |
Information |
| PC-62402 |
UK 356618
|
UK 356618 is a potent and selective MMP3 inhibitor with IC50 of 5.9 nM, shows >140-fold less potent against MMP-1 (IC50=51000 nM), MMP-2 (IC50=1790 nM), MMP-9 (IC50=840 nM) and MMP-14 (IC50=1900 nM). |
| PC-61898 |
proMMP9-IN-3c
proMMP-9 inhibitor
|
proMMP9-IN-3c is a potent and specific inhibitor of the hemopexin-like domain of MMP-9 (proMMP-9) with Kd of 320 nM. |
| PC-61392 |
Otaplimastat
|
Otaplimastat is a potent matrix metalloproteinase (MMP) inhibitor. |
| PC-70316 |
ND-336
MMP2, 3, 9 inhibitor
|
ND-336 (ND336) is a potent, selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively. |
| PC-61148 |
PF-152
MMP13 inhibitor
|
PF-152 is a potent, highly selective and orally bioavailable MMP13 inhibitor with Ki of 1.5 nM, with no activity against MMP3 (Ki>10 uM). |
| PC-60981 |
BK-1361
ADAM8 inhibitor
|
BK-1361 (BK1361, cyclo-RLsKDK) is a cyclic peptide with RLsKDK (s=D-serine) that functions as a potent, selective inhibitor of ADAM8 with IC50 of 120 nM. |
| PC-60174 |
ND-378
MMP-2 inhibitor
|
ND-378 (ND378) is a potent, selective MMP-2 inhibitor with Ki of 230 nM. |
| PC-45629 |
NAMI-A
MMP-2/9 inhibitor
|
A ruthenium anticancer agent that has a selective effect on lung metastases of solid metastasizing tumors. |
| PC-42562 |
CTS-1027
MMP inhibitor
|
CTS-1027 (RS-130830) is a potent, selective, broad-spectrum MMP inhibitor with Ki of <9 nM for MMP2, 3, 8, 9, 12, 13 and 14, but not MMP1 and 7. |
| PC-42086 |
TAPI-2
ADAM17 inhibitor
|
TAPI-2 is a broad-spectrum inhibitor of TNF-α converting enzyme (TACE, ADAM17), ADAMs, and other MMPs, inhibits ADAM8, 10, 12, and TACE with Ki values of 10, 3, 100, and 0.12 uM, respectively. |
| PC-42904 |
Marimastat
MMP inhibitor
|
Marimastat (BB-2516, TA-2516) is a potent, broad spectrum MMP inhibitor for MMP9/1/2/14/7 with IC50 of 3/5/6/9/13 nM, respectively. |
| PC-22480 |
PD166793
MMP inhibitor
|
PD166793 (PD-166793 ) is a selective, orally active broad spectrum inhibitor of MMPs with IC50 of 4, 7, and 8 nM for MMP-2, MMP-3 and MMP-13, inhibits MMP-1, MMP-7 and MMP-9 with IC50 of 6-8 uM. |
