| Cat. No. |
Product Name |
Information |
| PC-62941 |
DB04760
MMP-13 inhibitor
|
DB04760 is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with IC50 of 8 nM, displays high selectivity over other MMPs. |
| PC-62940 |
CL-82198
MMP-13 inhibitor
|
CL-82198 is a potent, selective inhibitor of MMP-13 (89% inhibition at 10 ug/mL), displays no activity at MMP-1, MMP-9 and TACE, significantly reduces the migration of LS174 cells by 55% at 10 uM.. |
| PC-62939 |
CL-82198 hydrochloride
MMP-13 inhibitor
|
CL-82198 is a potent, selective inhibitor of MMP-13 (89% inhibition at 10 ug/mL), displays no activity at MMP-1, MMP-9 and TACE, significantly reduces the migration of LS174 cells by 55% at 10 uM.. |
| PC-62732 |
ML115
MMP-2 inhibitor
|
ML115 is a novel bone-seeking, bisphosphonate based MMP-2 specific inhibitor (BMMPI), spares the activity of other MMPs including MMP-9. |
| PC-62731 |
ML104
MMP-2 inhibitor
|
ML104 is a "bone-seeking" bisphosphonate based MMP-2 specific inhibitor (BMMPI), spares the activity of other MMPs including MMP-9. |
| PC-62402 |
UK 356618
|
UK 356618 is a potent and selective MMP3 inhibitor with IC50 of 5.9 nM, shows >140-fold less potent against MMP-1 (IC50=51000 nM), MMP-2 (IC50=1790 nM), MMP-9 (IC50=840 nM) and MMP-14 (IC50=1900 nM). |
| PC-61898 |
proMMP9-IN-3c
proMMP-9 inhibitor
|
proMMP9-IN-3c is a potent and specific inhibitor of the hemopexin-like domain of MMP-9 (proMMP-9) with Kd of 320 nM. |
| PC-61392 |
Otaplimastat
|
Otaplimastat is a potent matrix metalloproteinase (MMP) inhibitor. |
| PC-70316 |
ND-336
MMP2, 3, 9 inhibitor
|
ND-336 (ND336) is a potent, selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively. |
| PC-61148 |
PF-152
MMP13 inhibitor
|
PF-152 is a potent, highly selective and orally bioavailable MMP13 inhibitor with Ki of 1.5 nM, with no activity against MMP3 (Ki>10 uM). |
| PC-60981 |
BK-1361
ADAM8 inhibitor
|
BK-1361 (BK1361, cyclo-RLsKDK) is a cyclic peptide with RLsKDK (s=D-serine) that functions as a potent, selective inhibitor of ADAM8 with IC50 of 120 nM. |
| PC-60174 |
ND-378
MMP-2 inhibitor
|
ND-378 (ND378) is a potent, selective MMP-2 inhibitor with Ki of 230 nM. |
