| Cat. No. |
Product Name |
Information |
| PC-42708 |
GNE-493
PI3K/mTOR inhibitor
|
GNE-493 (GNE493) is a potent, selective dual pan-PI3K/mTOR inhibitor with IC50 of 3.4/12/16/16/32 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ/mTOR. |
| PC-42544 |
AZD6482
PI3Kβ inhibitor
|
AZD6482 (KIN193) is a potent, selective and ATP competitive PI3Kβ inhibitor with IC50 of 10 nM. |
| PC-42233 |
IPI-549
PI3Kγ inhibitor
|
Eganelisib (IPI-549) is a potent, highly selective, orally active inhibitor of PI3Kγ with IC50 of 16 nM, displays >100-fold selectivity over other lipid and protein kinases (PI3Kα IC50=3.2 uM, PI3Kβ IC50=3.5 uM, PI3Kδ IC50>8.4 uM). |
| PC-44791 |
Voxtalisib
PI3K inhibitor
|
Voxtalisib (XL765, SAR245409) is a potent, highly selective ATP-competitive inhibitor of class I PI3Ks with IC50s of 39/110/43/9 nM for p110α/p110β/p110δ/p120γ. |
| PC-42796 |
GNE-477
PI3K/mTOR inhibitor
|
GNE-477 is a potent, dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Ki of 21 nM for mTOR. |
| PC-42329 |
PI-103 hydrochloride
PI3K/mTOR inhibitor
|
PI-103 hydrochloride is a potent, dual class I PI3K/mTOR inhibitor with IC50 of 2/3/3/15/ for p110α/β/δ/γ, respectively. |
| PC-42328 |
PI-103
PI3K/mTOR inhibitor
|
PI-103 is a potent, dual class I PI3K/mTOR inhibitor with IC50 of 2/3/3/15/ for p110α/β/δ/γ, respectively. |
| PC-45837 |
Dactolisib
PI3K/mTOR inhibitor
|
Dactolisib (NVP-BEZ235) is a potent, dual ATP-competitive pan-class I PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM, respectively. |
| PC-45071 |
Seletalisib
PI3Kδ inhibitor
|
Seletalisib (UCB-5857) is a potent, ATP-competitive, and selective PI3Kδ inhibitor with IC50 of 12 nM. |
| PC-42442 |
Wortmannin
PI3K inhibitor
|
Wortmannin (SL-2052, KY-12420) is a potent PI3K inhibitor with IC50 of 3 nM, does not inhibit PI4K activity. |
| PC-42925 |
PI-3065
p110δ inhibitor
|
PI-3065 is a potent inhibitor of PI3K p110δ with IC50/Ki values of 5/1.5 nM respectively. |
| PC-45869 |
ZSTK474
PI3K inhibitor
|
ZSTK474 (ZSTK-474) is a potent inhibitor of class I PI3K isoforms with IC50 of 17 nM, 53 nM, and 6 nM for p110β, p110γ, and p110δ, respectively. |
