Cat. No. |
Product Name |
Information |
PC-21948 |
PIK-108
p110β inhibitor
|
PIK-108 is a potent, selective and allosteric PI3K p110β inhibitor with IC50 of 57 nM, 45-fold selective over PI3Kα (IC50=2600 nM). |
PC-21947 |
PI3Kα H1047R inhibitor 17
H1047R PI3Kα inhibitor
|
PI3Kα H1047R inhibitor 17 is a potent, selective H1047R PI3Kα mutant inhibitor with IC50 of 1 nM (inhibition of pAKT formation), without effect on PI3Kα WT. |
PC-21944 |
GSK2636771
PI3Kβ inhibitor
|
GSK2636771 is a potent, selective and orally bioavailable inhibitor of PI3Kβ with Ki/IC50 of 0.89/5.2 nM, respectively. |
PC-20451 |
PITCOIN2
PI3KC2α inhibitor
|
PITCOIN2 (LU-06-006) is a potent selective PI3KC2α inhibitor with IC50 of 126 nM, has selectivity against PI3KC2γ but shows micromolar activity on PI3KC2β. |
PC-42943 |
TGR-1202 R-enantiomer
|
TGR-1202 R-enantiomer is is the less active enantiomer of TGR-1202 (Umbralisib), TGR-1202 is a potent, selective, orally available PI3Kδ inhibitor with IC50 of 22 nM.. |
PC-42881 |
PI3K-IN-1
|
PI3K-IN-1 is a potent inhibitor of PI3K, extracted from patent WO2012103524 A2 and WO2013147649 A2.. |
PC-42647 |
PI3Kγ inhibitor 1
|
A potent PI3Kγ inhibitor.. |