Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-PI3K/Akt/mTOR Pathway-PI3K

Request The Product List ofPI3K PI3K

Cat. No. Product Name Information
PC-60057

Gedatolisib

PI3K/mTOR inhibitor

Gedatolisib (PF-05212384, PKI-587) is a highly potent, selective, dual PI3K/mTOR inhibitor with IC50 of 0.4/6/8/6/1.6 nM for PI3Kα/β/γ/δ/mTOR, respectively.
PC-45643

GSK-2269557

PI3Kδ inhibitor

Nemiralisib (GSK-2269557) is a highly potent and selective inhibitor of PI3Kδ (pKi=9.9).
PC-45597

3-Methyladenine

PI3K inhibitor

3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 uM and 60 uM in HeLa cells.
PC-45820

GDC-0941

PI3K inhibitor

Pictilisib (GSC-0941) is a potent, selective, orally bioavailable inhibitor of class I PI3Ks with IC50 of 3/33/3/75 nM for p110α/β/γ/δ, respectively.
PC-45782

GDC-0941 dimethanesulfonate

PI3K inhibitor

Pictilisib dimethanesulfonate (GSC-0941) is a potent, selective, orally bioavailable inhibitor of class I PI3Ks with IC50 of 3/33/3/75 nM for p110α/β/γ/δ, respectively.
PC-45950

NVP-BKM120

PI3K inhibitor

NVP-BKM120 (BKM-120, Buparlisib) is a potent, selective, orally bioavailable inhibitor of class I PI3K isoforms with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/β/δ/γ, respectively.
PC-44217

NVP-BKM120 hydrochloride

PI3K inhibitor

NVP-BKM120 (Buparlisib) hydrochloride potent, selective, orally bioavailable inhibitor of class I PI3K isoforms with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/β/δ/γ, respectively.
PC-45766

GDC-0084

PI3K/mTOR inhibitor

Paxalisib (GDC-0084, RG7666) is a potent, selective, brain penetrant dual inhibitor of class I PI3Ks and mTOR with Ki of 2/46/3/10/70 nM for PI3Kα/β/δ/γ/mTOR, respectively.
PC-42311

AS-605240

PI3Kγ inhibitor

AS-605240 (AS605240) is a potent, selective, ATP-competitive, orally active PI3Kγ inhibitor with IC50 of 8 nM.
PC-45169

Duvelisib

PI3Kδ/γ inhibitor

Duvelisib (IPI-145, INK-1197) is a potent, selective PI3Kδ/γ inhibitor with Ki of 23 pM/243 pM, IC50 of 1 nM/50 nM.
PC-42319

TG100-115

PI3Kγ/δ inhibitor

TG100-115 (TG100115) is a potent, selective PI3Kγ/δ with IC50 of 83/235 nM, respectively.
PC-42325

TGX-221

p110β inhibitor

TGX-221 is a potent, selective PI3K p110β inhibitor with IC50 of 8.5 nM.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com