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Cat. No. Product Name Information
PC-62886

GNE-293

PI3Kδ inhibitor

GNE-293 is a potent and selective PI3Kδ inhibitor with Ki of 0.47 nM, displays 256, 420, 219-fold selectivity over PI3Kα, PI3Kβ, PI3Kγ, respectively.
PC-62843

PI3Kα-IN-4h

PI3Kα inhibitor

PI3Kα-IN-4h is a potent, selective, ATP-competitive dual PI3Kα/mTOR inhibitor with IC50 of 0.5/104 nM respectively.
PC-62838

PI3Kα-IN-5

PI3Kα inhibitor

PI3Kα-IN-5 is a potent, selective PI3Kα inhibitor with enzyme IC50 and cell IC50 of 6 nM and 87 nM respectively, exhibits 100-fold selectivity over PI3Kβ.
PC-62830

PI3K-IN-8q

p110α/p110δ inhibitor

PI3K-IN-8q is a potent, selective dual p110α/p110δ inhibitor with Ki app of 3.3/8.36 nM respectively.
PC-62806

PI3Kδ-IN-7n

PI3Kδ inhibitor

PI3Kδ-IN-7n is a highly potent and selective PI3Kδ inhibitor with IC50 of 0.9 nM, displays high selectivity (>1,500-fold) over PI3Kα, PI3Kβ, PI3Kγ (IC50>1.5 uM).
PC-62708

PI3K-IN-16

PI3Kβ/δ inhibitor

PI3K-IN-16 is a potent and selective, orally bioavailable PI3Kβ and PI3Kδ inhibitor with cell IC50 of 12 nM (in PTEN null MDA-MB-468 cell) and 47 nM (in Jeko-1 B-cell), respectively.
PC-61959

DS-7423

PI3K/mTOR inhibitor

DS-7423 is a novel potent, small-molecule dual inhibitor of PI3K/mTOR with IC50 of 15.6, 1143, 249, 262 and 34.9 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR  respectively.
PC-61742

ST-162

MAPK/PI3K inhibitor

ST-162 is a potent, bifunctional MAPK/PI3K antagonist with IC50 of 191 nM and 398 nM for PI3Kα and MEK1, respectively.
PC-61741

ST-168

MEK/PI3K inhibitor

ST-168 is a novel potent, orally available MEK/PI3K bifunctional inhibitor with IC50 of 182, 69.2, 1482, 2293, and 41.7 nM for MEK1, PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ, respectively.
PC-61135

PI3Kβ/δ inhibitor 20a

PI3Kβ/δ inhibitor

PI3Kβ/δ inhibitor 20a is a potent, highly selective PI3Kβ/δ inhibitor with IC50 of 7.8/5.3 nM respectively, with liitle to no activity on PI3Kα/γ (IC50=850/>10,000 nM).
PC-61127

PI3Kδ inhibitor 52

ZUN64390 is a potent, selective, and efficacious PI3Kδ inhibitor with IC50 of 1.7 nM, >100-fold selectivitity over PI3Kγ/α/β.
PC-60983

AMG511

PI3K inhibitor

AMG511 (AMG-511) potent, efficacious, and orally available pan class I PI3K inhibitor with Ki of 4/6/2/1 nM for PI3Kα/β/δ/γ, respectively.

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