| Cat. No. |
Product Name |
Information |
| PC-42315 |
IC-87114
PI3Kδ inhibitor
|
IC-87114 (IC87114) is a potent and selective PI3Kδ inhibitor with IC50 of 0.5 uM. |
| PC-42326 |
SF2523
PI3K/BRD4 inhibitor
|
SF2523 is a potent, dual inhibitor of PI3K and BRD4 with IC50 of 241, 34, 158 nM for BRD4 (BD1), PI3Kα and PI3Kγ, respectively. |
| PC-45394 |
Leniolisib
PI3Kδ inhibitor
|
Leniolisib (CDZ173) is a potent and selective PI3Kδ inhibitor with biochemical IC50 of 11 nM. |
| PC-42518 |
PIK-294
p110δ inhibitor
|
PIK-294 is a highly potent, selective p110δ inhibitor with IC50 of 10 nM, shows 1000-, 49- and 16-fold less potent to PI3Kα/β/γ. |
| PC-42513 |
Omipalisib
PI3K/mTOR inhibitor
|
Omipalisib (GSK2126458) is a highly potent dual inhibitor PI3K/mTOR inhibitor with app Ki of 19/130/24/60/180/300 nM for p110α/p110β/p110γ/p110δ/mTORC1/mTORC2 respectively. |
| PC-42133 |
PF-04979064
PI3K/mTOR inhibitor
|
PF-04979064 is a highly potent and selective, dual PI3K/mTOR inhibitor with Ki of 0.13, 0.111, 0.122 and 1.42 nM for PI3Kα, PI3Kγ, PI3Kδ and mTOR, respectively. |
| PC-42310 |
LY294002
PI3K inhibitor
|
LY294002 is a classic, broad-spectrum PI3K inhibitor with IC50 of 0.5/0.57/0.97 uM for PI3Kα/δ/β, respectively. |
| PC-23245 |
Menadione sodium bisulfite
Vps34 inhibitor
|
Menadione sodium bisulfite (MSB) is a water-soluble form of vitamin K precursor menadione, suppresses prostate cancer growth by targeting the kinase VPS34 (phosphatidylinositol 3-kinase catalytic subunit type 3). |
| PC-23222 |
CHF6523
PI3Kδ inhibitor
|
CHF6523 is a potent, selective and inhaled PI3Kδ inhibitor with potential for treatment of Chronic obstructive pulmonary disease (COPD). |
| PC-23119 |
AS041164
PI3Kγ inhibitor
|
AS041164 is a potent, selective and orally bioavailable PI3Kγ inhibitor with IC50 of 70 nM, blocks RANTES-induced chemotaxis and reduces the level of AKT phosphorylation. |
| PC-23007 |
PITCOIN1
PI3KC2α inhibitor
|
PITCOIN1 is a potent, highly selective inhibitor of class II alpha PI3K (PI3K-C2α) with IC50 of 100 nM, with no activity against class I and III PI3Ks. |
| PC-23006 |
PI-701
PI3KC2β inhibitor
|
PI-701 (YM185453) is a selective inhibitor of class II PI3KC2β isoform with IC50 of 528 nM, does not display activity toward PI3K class I isoforms. |
