| Cat. No. |
Product Name |
Information |
| PC-60566 |
IPI-443
p110δ/γ inhibitor
|
A potent, selective, orally active p110δ/γ PI3K dual inhibitor with cellular IC50 of 0.29 and 7.1 nM, respectively. |
| PC-60565 |
IPI-3063
p110δ inhibitor
|
IPI-3063 is apotent, and selective p110δ PI3K inhibitor with IC50 of 0.1 nM in cell-based assays. |
| PC-60527 |
Parsaclisib
PI3Kδ inhibitor
|
Parsaclisib (INCB050465) is a potent and highly selective PI3Kδ inhibitor with IC50 of < 1 nM (SPA). |
| PC-60447 |
LAS191954
PI3Kδ inhibitor
|
LAS191954 is a potent, selective, orally bioavailable PI3Kδ inhibitor with IC50 of 2.6 nM. |
| PC-60413 |
SF-1126
|
SF-1126 is a pan PI3K/BRD4 inhibitor, RGDS-conjugated LY294002 prodrug that exhibits increased solubility and binds to specific integrins. |
| PC-60392 |
SN-32976
PI3K/mTOR inhibitor
|
SN-32976 is a novel, potent and selective class I PI3K and mTOR inhibitor with IC50 of 15.1/461/110/134/194 nM for PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ/mTOR, respectively. |
| PC-60391 |
BL-140
p110β inhibitor
|
BL-140 is a potent, specific p110β inhibitor with IC50 of 5.74 nM. |
| PC-70200 |
MTX-211
PI3K/EGFR inhibitor
|
MTX-211 is a first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases with IC50 of <100 nM. |
| PC-60176 |
INCB040093
PI3Kδ inhibitor
|
Dezapelisib (INCB040093) is a potent, selective, orally available PI3Kδ inhibitor with IC50 of 31 nM. |
| PC-60166 |
GDC-0326
PI3Kα inhibitor
|
GDC0326 (GDC-0326) is a potent, selective, orally available PI3Kα inhibitor with Ki of 0.2 nM. |
| PC-70090 |
GSK-2292767
PI3Kδ inhibitor
|
GSK-2292767 is a highly potent and selective inhibitor of PI3Kδ (pKi=10.1). |
| PC-60057 |
Gedatolisib
PI3K/mTOR inhibitor
|
Gedatolisib (PF-05212384, PKI-587) is a highly potent, selective, dual PI3K/mTOR inhibitor with IC50 of 0.4/6/8/6/1.6 nM for PI3Kα/β/γ/δ/mTOR, respectively. |
