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Cat. No. Product Name Information
PC-35114

N205

Antimalarial

N205 is a novel anti-malaria compound with in vitro IC50 of 1.3 nM against Plasmodium falciparum (3D7).
PC-63381

Tafenoquine

Antimalarial

Tafenoquine (SB-252263, WR 238605) is a long-acting, orally active anti-malarial agent to prevent malaria that is holoendemic for Plasmodium falciparum.
PC-63378

Cipargamin

Antimalarial

Cipargamin (KAE609, NITD609) is a fast-acting, potent antimalarial agent that inhibits blood-stage activity in vitro against a panel of culture-adapted P. falciparum strains with IC50 of 0.5-1.4 nM.
PC-63332

Bm-MPK1-IN-15b

Bm-MPK1-IN-15b is a potent, orally bioavailable inhibitor of B. malayi stress-activated kinase Bm-MPK1 with IC50 of 24 nM.
PC-63237

DNDI-8219

DNDI-8219 is a novel potent, orally active antileishmanial agent with IC50 of 0.19 uM against Leishmania donovani (L. don).
PC-62987

Artefenomel

Antimalarial

Artefenomel (OZ439) is a novel, next-generation antimalarial ozonide that demonstrates high potentcy against P. falciparum in vitro and P. berghei in vivo (K1/NF54, IC50=2.0/3.2 nM).
PC-62611

JPC-3210

Antimalarial

JPC-3210 is a potent antimalarial agent with IC50 of 2.5-19 nM, remains activity against multidrug-resistant Plasmodium falciparum lines with little cytotoxicity in mammalian cell lines.
PC-62608

FR900098 sodium

Antimalarial

FR900098 sodium is a derivative of fosmidomycin that inhibits DOXP reductoisomerase, demonstrates antimalarial activity with IC50 of 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively.
PC-62150

KDU731

Cryptosporidium PI4K inhibitor

KDU731 is a potent, selective parasite Cryptosporidium lipid kinase PI4K (phosphatidylinositol-4-OH kinase) inhibitor with IC50 of 25 nM, displays >50-fold selectivity window against the human PI4K IIIβ homologue.
PC-61904

SJ733

PfATP4 inhibitor

SJ733 (SJ000557733, SJ-557733) is an anti-malarial compound that targets ATP4 (PfATP4), a cation-transporting ATPase responsible for maintaining low intracellular Na(+) levels in the parasite.
PC-61697

KAI407

Antimalarial

KAI407 is a potent, non-8-aminoquinoline antamalarial compound that kills Plasmodium cynomolgi early dormant liver stage parasites (IC50=0.69 uM for hypnozoites, IC50=0.64 uM for developing liver stages).
PC-61378

Ganaplacide

Antimalarial

Ganaplacide (KAF156, GNF-156) is a novel antimalarial clinical candidate that shows blood schizonticidal activity with IC50 of 6-17.4 nM against P falciparum drug-sensitive and drug-resistant strains.

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