| Cat. No. |
Product Name |
Information |
| PC-63332 |
Bm-MPK1-IN-15b
|
Bm-MPK1-IN-15b is a potent, orally bioavailable inhibitor of B. malayi stress-activated kinase Bm-MPK1 with IC50 of 24 nM. |
| PC-63237 |
DNDI-8219
|
DNDI-8219 is a novel potent, orally active antileishmanial agent with IC50 of 0.19 uM against Leishmania donovani (L. don). |
| PC-62611 |
JPC-3210
Antimalarial
|
JPC-3210 is a potent antimalarial agent with IC50 of 2.5-19 nM, remains activity against multidrug-resistant Plasmodium falciparum lines with little cytotoxicity in mammalian cell lines. |
| PC-62608 |
FR900098 sodium
Antimalarial
|
FR900098 sodium is a derivative of fosmidomycin that inhibits DOXP reductoisomerase, demonstrates antimalarial activity with IC50 of 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively. |
| PC-62150 |
KDU731
Cryptosporidium PI4K inhibitor
|
KDU731 is a potent, selective parasite Cryptosporidium lipid kinase PI4K (phosphatidylinositol-4-OH kinase) inhibitor with IC50 of 25 nM, displays >50-fold selectivity window against the human PI4K IIIβ homologue. |
| PC-61904 |
SJ733
PfATP4 inhibitor
|
SJ733 (SJ000557733, SJ-557733) is an anti-malarial compound that targets ATP4 (PfATP4), a cation-transporting ATPase responsible for maintaining low intracellular Na(+) levels in the parasite. |
| PC-61378 |
Ganaplacide
Antimalarial
|
Ganaplacide (KAF156, GNF-156) is a novel antimalarial clinical candidate that shows blood schizonticidal activity with IC50 of 6-17.4 nM against P falciparum drug-sensitive and drug-resistant strains. |
| PC-61006 |
GNF-Pf-5660
|
GNF-Pf-5660 is an antimalarial candidate that demonstrates potent blood-stage and transmission-blocking activity, shows potent ABS activity (IC50 <25 nM) against drug-sensitive 3D7 and multidrug-resistant Dd2 parasites. |
| PC-60489 |
MMV019313
|
MMV019313 (MMV 019313, MMV-019313) is a potent, specific malaria bifunctional farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) inhibitor with IC50 of 330 nM. |
| PC-60458 |
DSM265
PfDHODH inhibitor
|
DSM265 is a potent, highly selective, long-duration and orally bioavailable malaria DHODH (PfDHODH) inhibitor with IC50 of 0.01 ug/mL. |
| PC-60316 |
SCYX-7158
Anti-parasite
|
SCYX-7158 (AN-5568, Acoziborole) is an orally-active, CNS permeable benzoxaborole antiprotozoal agent. |
| PC-60315 |
GNF-6702
|
GNF-6702 (GNF6702) is a selective, non-competitive inhibitor of the kinetoplastid proteasome, inhibits the chymotrypsin-like activity of the T. cruzi proteasome with IC50 of 35 nM. |
