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Cat. No. Product Name Information
PC-62611

JPC-3210

Antimalarial

JPC-3210 is a potent antimalarial agent with IC50 of 2.5-19 nM, remains activity against multidrug-resistant Plasmodium falciparum lines with little cytotoxicity in mammalian cell lines.
PC-62608

FR900098 sodium

Antimalarial

FR900098 sodium is a derivative of fosmidomycin that inhibits DOXP reductoisomerase, demonstrates antimalarial activity with IC50 of 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively.
PC-62150

KDU731

Cryptosporidium PI4K inhibitor

KDU731 is a potent, selective parasite Cryptosporidium lipid kinase PI4K (phosphatidylinositol-4-OH kinase) inhibitor with IC50 of 25 nM, displays >50-fold selectivity window against the human PI4K IIIβ homologue.
PC-61904

SJ733

PfATP4 inhibitor

SJ733 (SJ000557733, SJ-557733) is an anti-malarial compound that targets ATP4 (PfATP4), a cation-transporting ATPase responsible for maintaining low intracellular Na(+) levels in the parasite.
PC-61378

Ganaplacide

Antimalarial

Ganaplacide (KAF156, GNF-156) is a novel antimalarial clinical candidate that shows blood schizonticidal activity with IC50 of 6-17.4 nM against P falciparum drug-sensitive and drug-resistant strains.
PC-61006

GNF-Pf-5660

GNF-Pf-5660 is an antimalarial candidate that demonstrates potent blood-stage and transmission-blocking activity, shows potent ABS activity (IC50 <25 nM) against drug-sensitive 3D7 and multidrug-resistant Dd2 parasites.
PC-60489

MMV019313

MMV019313 (MMV 019313, MMV-019313) is a potent, specific malaria bifunctional farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) inhibitor with IC50 of 330 nM.
PC-60458

DSM265

PfDHODH inhibitor

DSM265 is a potent, highly selective, long-duration and orally bioavailable malaria DHODH (PfDHODH) inhibitor with IC50 of 0.01 ug/mL.
PC-60316

SCYX-7158

Anti-parasite

SCYX-7158 (AN-5568, Acoziborole) is an orally-active, CNS permeable benzoxaborole antiprotozoal agent.
PC-60315

GNF-6702

GNF-6702 (GNF6702) is a selective, non-competitive inhibitor of the kinetoplastid proteasome, inhibits the chymotrypsin-like activity of the T. cruzi proteasome with IC50 of 35 nM.
PC-45380

Closantel

FICD inhibitor

Closantel (FICD inhibitor C22) is a veterinary anthelmintic with known proton ionophore activities, also is a small molecule inhibitor of the AMP transferase FICD with IC50 of 7.27 uM.
PC-45409

Pyrimethamine

Pyrimethamine is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties, interferes with the regeneration of tetrahydrofolic acid from dihydrofolate by competitively inhibiting DHFR, has also been found to reduce the expression of SOD1.

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