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Cat. No. Product Name Information
PC-23267

DDD489

CpKRS inhibitor

DDD489 is a potent, selective Cryptosporidium lysyl-tRNA synthetase (CpKRS) inhibitor with IC50 of 0.85 uM, and C. parvum EC50 of 0.04 uM, shows anti-cryptosporidials activity.
PC-23225

AR102

Schistosomes inhibitor

AR102 is a potent, selective, and broad-spectrum activity against schistosome species.
PC-23030

MMV665806

Falcilysin inhibitor, Antimalarial

MMV665806 is a small molecule antimalarial compound, bind to falcilysin (FLN) with KD of 7.33 uM and inhibits FLN proteolytic activity with IC50 of 5.9 uM.
PC-23029

MMV000848

Falcilysin inhibitor, PfPNP inhibitor

MMV000848 is a small molecule inhibitor of P. falciparum purine nucleoside phosphorylase (PfPNP, KD=1.52 uM) with EC50 of 0.1 uM against Plasmodium falciparum, also inhibits falcilysin (FLN) proteolytic activity.
PC-23028

MK-4815 hydrochloride

Falcilysin inhibitor, Antimalarial

MK-4815 hydrochloride is an orally active small molecule with antimalarial activity, inhibits P. falciparum 3D7 growth with IC50 of 0.03 ug/mL, inhibits falcilysin (FLN) proteolytic activity.
PC-23027

MK-4815

Falcilysin inhibitor, Antimalarial

MK-4815 is an orally active small molecule with antimalarial activity, inhibits P. falciparum 3D7 growth with IC50 of 0.03 ug/mL, inhibits falcilysin (FLN) proteolytic activity.
PC-22969

UCT594

PfPI4K inhibitor

UCT594 is a highly potent, selective Plasmodium phosphatidylinositol 4-kinase (PfPI4K) inhibitor, inhibits P. falciparum asexual blood-stage activity.
PC-22800

SW584

Pf20Sβ5 inhibitor

SW584 is a potent, species-selective, orally active inhibitor of P. falciparum proteasome β5 active site (Pf20Sβ5) with IC50 of 5.8 nM, shows antimalarial activity with EC50 of 3 nM (Pf3D7 and PfDd2).
PC-22744

MMV026468

Antimalarial

MMV026468 is a highly potent, picomolar inhibitor of blood-stage Plasmodium falciparum, targets MEP isoprenoid precursor biosynthesis, inhibits first MEP enzyme DXS or steps prior to DXS such as regulation of the MEP pathway.
PC-22743

MMV1580853

Antimalarial

MMV1580853 (BPH-1358) is a potent and exceedingly fast-acting blood-stage antimalarial, inhibits human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor with IC50s of 1.8 μM and 110 nM, respectively.
PC-22690

MIPS2673

Parasite M1 aminopeptidase inhibitor

MIPS2673 is a potent selective inhibitor of Plasmodium M1 aminopeptidase with Ki of 211 nM and 6.4 nM for PfA-M1 and PvA-M1, demonstrates antimalarial activity against a panel of drug-resistant P. falciparum strains.
PC-22543

WEHI-991

PfSTART1 inhibitor

WEHI-991 (W-991) is a potent small molecule inhibitor of PfSTART1 with antiparasitic activity EC50 of 7 nM for Pf 3D7, binds to PfSTART1(WT) with KD of 10 nM, inhibits ring-stage development of Plasmodium falciparum.

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