| Cat. No. |
Product Name |
Information |
| PC-27175 |
UCB-9721
TgMyoA inhibitor
|
UCB-9721 is a potent inhibitor of T. gondii MyoA (TgMyoA) with IC50 of 31 nM, a class XIV myosin motor of apicomplexan parasites, inhibits TgMyoA actin-activated ATPase activity. |
| PC-27146 |
Artesunate
P. falciparum EXP1 inhibitor, STAT3 inhibitor
|
Artesunate is an antimalarial and potent, hematin-dependent inhibitor of P. falciparum exported protein 1 (EXP1, PfMGST) with IC50 of 2.05 nM, inhibits EXP1 glutathione transferase activity toward hematin, also is a potential inhibitor of STAT-3. |
| PC-27145 |
Artemether
Antimalarial
|
Artemether is a potent and rapidly acting blood schizontocide, interferes with the growth of parasites in the red blood cells of the human body, is a semi-synthetic derivative of artemisinin. |
| PC-27144 |
Praziquantel
Anthelmintic
|
Praziquantel (Embay 8440) is an orally active, broadly effective anthelmintic for trematodes and cestodes infections such as schistosomiasis, taeniasis, and cysticercosis. |
| PC-27143 |
DW-3-15
Antischistosomal
|
DW-3-15 is a praziquantel and artesunate conjugate and effective anti-schistosomal agent, inhibits both juvenile and adult Schistosoma japonicumin through SjHAT1 inhibition, exhibits good worm killing activity both in vitro and in vivo. |
| PC-27033 |
PfKRS1 inhibitor 30
PfKRS1 inhibitor
|
PfKRS1 inhibitor 30 is a potent selective inhibitor of P. falciparum lysyl-tRNA synthetase (PfKRS1) with pIC50 of 6.9, >1,000-fold selectivity for PfKRS1 over the human enzyme, exhibits potency against Pfalciparum (3D7) asexual blood stage with EC50 of 6 nM. |
| PC-26852 |
SLU-2633
Cryptosporidium parvum inhibitor
|
SLU-2633 is an orally efficacious anticryptosporidial triazolopyridazine with EC50 of 0.17 uM against Cryptosporidium parvum, exhibits fast-killing anticryptosporidial properties. |
| PC-26851 |
MMV665917
Cryptosporidium parvum inhibitor
|
MMV665917 is an orally active piperazine-based compound with high selectivity for the blood stages of malaria parasites and for Cryptosporidium species (Cryptosporidium parvum, EC90=15 uM). |
| PC-26820 |
Borrelidin
Threonyl-tRNA synthetase inhibitor
|
Borrelidin is a small molecule nitrile-containing macrolide inhibitor of bacterial and eukaryal threonyl-tRNA synthetase (ThrRS), inhibits protein synthesis, also shows stage-specific growth inhibition for Plasmodium falciparum. |
| PC-26689 |
WIN 4-88
CpCDPK1 inhibitor
|
WIN 4-88 is a potent small molecule inhibitor of Cryptosporidium parvum Calcium-dependent protein kinase 1 (CpCDPK1) with IC50 of 56 nM, exhibits growth inhibition of zoonotic C. parvum, anthroponotic C. parvum and C. hominis Tu502 with EC50 of 42, 30 and 62 nM respectively. |
| PC-26680 |
P218 hydrochloride
PfDHFR inhibitor
|
P218 hydrochloride is a highly potent inhibitor of Plasmodium falciparum dihydrofolate reductase (PfDHFR) with Ki of 0.54 nM for quadruple mutant P. falciparum DHFR, inhibits wild-type P. falciparum (TM4) and quadruple mutant P. falciparum (V1/S) with IC50 of 4.6 nM and 56 nM. |
| PC-26679 |
PfDHFR inhibitor P218
PfDHFR inhibitor
|
PfDHFR inhibitor P218 is a highly potent inhibitor of Plasmodium falciparum dihydrofolate reductase (PfDHFR) with Ki of 0.54 nM for quadruple mutant P. falciparum DHFR, inhibits wild-type P. falciparum (TM4) and quadruple mutant P. falciparum (V1/S) with IC50 of 4.6 nM and 56 nM. |
