| Cat. No. |
Product Name |
Information |
| PC-25292 |
DNDI-VL-2098
Visceral leishmaniasis inhibitor
|
DNDI-VL-2098 is an orally effective preclinical drug candidate for visceral leishmaniasis (VL) with IC50 of 0.17 uM for L. infantum. |
| PC-25291 |
DNDI-0690
Visceral leishmaniasis inhibitor
|
DNDI-0690 is a clinical drug candidate for visceral leishmaniasis (VL), demonstrated excellent in vitro activity against three Old World and three New World cutaneous Leishmania strains (EC50<5 uM). |
| PC-25290 |
DNDI-5561
T. cruzi inhibitor
|
DNDI-5561 is a small molecule inhibitor of T. cruzi and L. infantum with IC50 of 38 uM and 0.2 uM. |
| PC-25202 |
BKI-1841
CpCDPK1 inhibitor
|
BKI-1841 is a highly potent, specific Cryptosporidium calcium-dependent protein kinase 1 (CDPK1) inhibitor with IC50 of 3 nM (CpCDPK1, C. parvum CDPK1) and EC50 of 0.7 uM against C. parvum parasites in Nanoluciferase assays. |
| PC-25201 |
BKI-1770
CpCDPK1 inhibitor
|
BKI-1770 is a highly potent, specific Cryptosporidium calcium-dependent protein kinase 1 (CDPK1) inhibitor with IC50 of 2 nM (CpCDPK1, C. parvum CDPK1) and EC50 of 0.5 uM against C. parvum parasites in Nanoluciferase assays. |
| PC-25200 |
BKI-1708
CpCDPK1 inhibitor
|
BKI-1708 is a highly potent, specific Cryptosporidium calcium-dependent protein kinase 1 (CDPK1) inhibitor with IC50 of 0.7 nM (CpCDPK1, C. parvum CDPK1) and EC50 of 0.4 uM against C. parvum parasites in Nanoluciferase assays. |
| PC-25134 |
T231
Antimalarial
|
T231 is the prodrug of T111, a potent acridone antimalarial inhibitor against blood, liver, and mosquito stages of malaria parasite. |
| PC-25133 |
T111
Antimalarial
|
T111 is a potent acridone antimalarial inhibitor against blood, liver, and mosquito stages of malaria parasite, inhibits mitochondrial electron transport chain, has IC50 of 0.028, 0.11 and 0.11 nM for P. falciparum strains Dd2, DR1, and DR4. |
| PC-25082 |
Piperaquine tetraphosphate tetrahydrate
Antimalarial
|
Piperaquine tetraphosphate tetrahydrate is a bisquinoline antimalarial agent. |
| PC-25081 |
Piperaquine phosphate
Antimalarial
|
Piperaquine phosphate is a bisquinoline antimalarial agent. |
| PC-25080 |
Piperaquine
Antimalarial
|
Piperaquine is a bisquinoline antimalarial agent. |
| PC-25005 |
ZY-19489
Antimalarial
|
Sutidiazine (Zintrodiazine, ZY-19489, MMV 253, AZ-13721412) is a novel antimalarial triaminopyrimidine compound with IC50 of 9 nM against sexual blood stage of Plasmodium falciparum (Pf). |
