| Cat. No. |
Product Name |
Information |
| PC-25290 |
DNDI-5561
T. cruzi inhibitor
|
DNDI-5561 is a small molecule inhibitor of T. cruzi and L. infantum with IC50 of 38 uM and 0.2 uM. |
| PC-25202 |
BKI-1841
CpCDPK1 inhibitor
|
BKI-1841 is a highly potent, specific Cryptosporidium calcium-dependent protein kinase 1 (CDPK1) inhibitor with IC50 of 3 nM (CpCDPK1, C. parvum CDPK1) and EC50 of 0.7 uM against C. parvum parasites in Nanoluciferase assays. |
| PC-25201 |
BKI-1770
CpCDPK1 inhibitor
|
BKI-1770 is a highly potent, specific Cryptosporidium calcium-dependent protein kinase 1 (CDPK1) inhibitor with IC50 of 2 nM (CpCDPK1, C. parvum CDPK1) and EC50 of 0.5 uM against C. parvum parasites in Nanoluciferase assays. |
| PC-25200 |
BKI-1708
CpCDPK1 inhibitor
|
BKI-1708 is a highly potent, specific Cryptosporidium calcium-dependent protein kinase 1 (CDPK1) inhibitor with IC50 of 0.7 nM (CpCDPK1, C. parvum CDPK1) and EC50 of 0.4 uM against C. parvum parasites in Nanoluciferase assays. |
| PC-25134 |
T231
Antimalarial
|
T231 is the prodrug of T111, a potent acridone antimalarial inhibitor against blood, liver, and mosquito stages of malaria parasite. |
| PC-25133 |
T111
Antimalarial
|
T111 is a potent acridone antimalarial inhibitor against blood, liver, and mosquito stages of malaria parasite, inhibits mitochondrial electron transport chain, has IC50 of 0.028, 0.11 and 0.11 nM for P. falciparum strains Dd2, DR1, and DR4. |
| PC-25082 |
Piperaquine tetraphosphate tetrahydrate
Antimalarial
|
Piperaquine tetraphosphate tetrahydrate is a bisquinoline antimalarial agent. |
| PC-25081 |
Piperaquine phosphate
Antimalarial
|
Piperaquine phosphate is a bisquinoline antimalarial agent. |
| PC-25080 |
Piperaquine
Antimalarial
|
Piperaquine is a bisquinoline antimalarial agent. |
| PC-25005 |
ZY-19489
Antimalarial
|
Sutidiazine (Zintrodiazine, ZY-19489, MMV 253, AZ-13721412) is a novel antimalarial triaminopyrimidine compound with IC50 of 9 nM against sexual blood stage of Plasmodium falciparum (Pf). |
| PC-24979 |
DMU759
TcKRS1 inhibitor
|
DMU759 is a specific inhibitor of T. cruzi lysyl-tRNA synthetase 1 (TcKRS1) with IC50 of 15 nM, demonstrates potent activity against T. cruzi (Sylvio X10/7A1strain) with EC50 of 14 nM. |
| PC-24978 |
DMU371
TcKRS1 inhibitor
|
DMU371 is a specific inhibitor of T. cruzi lysyl-tRNA synthetase 1 (TcKRS1) with IC50 of 185 nM, demonstrates potent activity against T. cruzi (Sylvio X10/7A1strain) with EC50 of 63 nM. |
