| Cat. No. |
Product Name |
Information |
| PC-38416 |
MMV688533
Antimalarial
|
MMV688533 is a potent antimalarial compound that displays fast parasite clearance in vitro and is not cross-resistant with known antimalarials, MMV688533 is highly potent against multiple P. falciparum strains with IC50 values in low nanomolar range (P. falciparum 3D7, IC50=1.9 nM). |
| PC-38402 |
Mivorilaner
Parasiticidal agent
|
Mivorilaner is a parasiticidal dihydroisoxazole compound. |
| PC-38367 |
Modoflaner
Antiparasitic agent
|
Modoflaner is an isophenylamide insecticide. Modoflaner may act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels |
| PC-38359 |
Fanotaprim
TgDHFR inhibitor
|
Fanotaprim (VYR-006) is a potent, selective Toxoplasma gondii DHFR (TgDHFR) inhibitor with IC50 of 1.6 nM, 200-fold selectivity over human DHFR (hDHFR), shows anti-parasiticidal activity in vitro and in vivo. |
| PC-73100 |
MMV675968
Antifungal agent
|
MMV675968 is a potent, small molecule inhibitor of Toxoplasma gondii (T. gondii) with IC50 of 0.02 uM, via the pathogen box. |
| PC-73056 |
TCMDC-135051
PfCLK3 inhibitor
|
TCMDC-135051 is a potent PfCLK3 inhibitor with IC50 of 40 nM. |
| PC-72991 |
AN7973
Parasite inhibitor
|
AN7973 (AN-7973) is a novel drug candidate for treatment of cryptosporidiosis, potently inhibits multiple C. parvum isolates and the C. hominis TU502 isolate in vitro. |
| PC-72957 |
Pyronaridine
Pf β-hematin inhibitor
|
Pyronaridine is a fast-acting (chloroquine-like) drug that has the demonstrated ability to inhibit P. falciparum β-hematin formation in vitro, suppress the selection of M5717-resistant mutants. |
| PC-72956 |
M5717
PfeEF2 inhibitor
|
Cabamiquine (DDD107498, M5717) is a potent, specific P. falciparum translation elongation factor 2 inhibitor (PfeEF2). |
| PC-72936 |
SBI-0797750
PfGluPho inhibitor
|
SBI-0797750 (SBI 0797750) is a potent, fully selective PfGluPho inhibitor with robust nanomolar activity against recombinant PfGluPho, PvG6PD, and P. falciparum blood-stage parasites. |
| PC-72859 |
PDE-I2
Anti-malaria
|
PDE-I2 is a potent and selective inhibitor of malaria proliferation with P. falciparum IC50 of 18 nM. |
| PC-72583 |
CTCB-405
TbPFK inhibitor
|
CTCB-405 (CTCB405) is a small molecule allosteric inhibitor of T. brucei phosphofructokinase (TbPFK) with IC50 of 0.18 uM, ITC Kd of 92 nM, no significant inhibition of human PFKs. |
