| Cat. No. |
Product Name |
Information |
| PC-72991 |
AN7973
Parasite inhibitor
|
AN7973 (AN-7973) is a novel drug candidate for treatment of cryptosporidiosis, potently inhibits multiple C. parvum isolates and the C. hominis TU502 isolate in vitro. |
| PC-72957 |
Pyronaridine
Pf β-hematin inhibitor
|
Pyronaridine is a fast-acting (chloroquine-like) drug that has the demonstrated ability to inhibit P. falciparum β-hematin formation in vitro, suppress the selection of M5717-resistant mutants. |
| PC-72956 |
M5717
PfeEF2 inhibitor
|
Cabamiquine (DDD107498, M5717) is a potent, specific P. falciparum translation elongation factor 2 inhibitor (PfeEF2). |
| PC-72936 |
SBI-0797750
PfGluPho inhibitor
|
SBI-0797750 (SBI 0797750) is a potent, fully selective PfGluPho inhibitor with robust nanomolar activity against recombinant PfGluPho, PvG6PD, and P. falciparum blood-stage parasites. |
| PC-72859 |
PDE-I2
Anti-malaria
|
PDE-I2 is a potent and selective inhibitor of malaria proliferation with P. falciparum IC50 of 18 nM. |
| PC-72583 |
CTCB-405
TbPFK inhibitor
|
CTCB-405 (CTCB405) is a small molecule allosteric inhibitor of T. brucei phosphofructokinase (TbPFK) with IC50 of 0.18 uM, ITC Kd of 92 nM, no significant inhibition of human PFKs. |
| PC-72540 |
MMV084978
PfAcAS inhibitor
|
MMV084978 (MMV 084978) is an antiplasmodial drug-like compound tageting Plasmodium falciparum acetyl-coenzyme A synthetase (PfAcAS), directly and selectively inhibit PfAcAS activity in vitro with IC50 of 370 nM. |
| PC-72539 |
MMV019721
PfAcAS inhibitor
|
MMV019721 (MMV019721) is an antiplasmodial drug-like compound tageting Plasmodium falciparum acetyl-coenzyme A synthetase (PfAcAS), directly and selectively inhibit PfAcAS activity in vitro with IC50 of 73 nM. |
| PC-72521 |
INE963
Antimalarial
|
INE963 (INE-963) is a potent and fast-acting blood-stage antimalarial, demonstrates potent cellular activity against Pf 3D7 with EC50 of 6 nM in Pf growth inhibition assay. |
| PC-72407 |
CTN1122
L-CK1.2 inhibitor
|
CTN1122 (CTN-1122) is a potent, selective Leishmaniacasein kinase 1 isoform 2 (CK1.2, L-CK1.2) with IC50 of 0.72 uM (LmCK1) and 0.8 uM (amastigotes L. major), antileishmanial compound. |
| PC-72339 |
MMV030084
Pf PKG inhibitor
|
MMV030084 (MMV-030084) is a potent, specific P. falciparum cGMP-dependent protein kinase (PKG) inhibitor (Kdapp=9-16 nM), inhibits invasion of P. berghei ANKA parasites into HepG2 liver cells with IC50 of 199 nM. |
| PC-38234 |
Parabulin
Parasite tubulin inhibitor
|
Parabulin is a novel potent, parasite-specific tubulin inhibitor, inhibits growth of parasites while displaying no effects on human cells. |
