| Cat. No. |
Product Name |
Information |
| PC-21377 |
Antitrypanosomal agent 10
Antitrypanosomal
|
Antitrypanosomal agent 10 is a potent, orally active antitrypanosomal compound, selectively inhibits the growth of parasites T. b. brucei, T. b. gambiense and T. b. rhodesiense with EC50 of 0.54, 0.13 and 1.14 uM, resepctively. |
| PC-21135 |
IMP-1002
NMT inhibitor
|
IMP-1002 (IMP1002) is a potent P. falciparum N-myristoyltransferase (PfNMT) inhibitor, potently inhibits parasite growth with EC50 of 34 nM (3D7 strain). |
| PC-21094 |
WEHI-518
PfPI4KIIIB inhibitor
|
WEHI-518 is a small molecule inhibitor of the parasite's phosphatidylinositol kinase PfPI4KIIIB, shows EC50 of 22 nM against blood-stage P. falciparum parasites. |
| PC-21087 |
MMV396797
PfPI4KIIIB inhibitor
|
MMV396797 is a small molecule inhibitor of the parasite's phosphatidylinositol kinase PfPI4KIIIB, block parasite protein secretion and export. |
| PC-20947 |
Cyanotriazole CT3
Parasite Topo II inhibitor
|
Cyanotriazole CT3 is a potent, selective, irreversible inhibitor of trypanosomal topoisomerase II, shows potent trypanocidal activity both in vitro and in vivo. |
| PC-20941 |
JC-229
TbRPA1 inhibitor
|
JC-229 is a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1 (TbRPA1), exhibits growth inhibition of T. brucei with EC50 of 6.6 uM. |
| PC-20587 |
ML276
PfG6PDH inhibitor
|
ML276 (ML 276) is a potent, selective inhibitor of Plasmodium falciparum glucose-6-phosphate dehydrogenase (PfG6PDH) with IC50 of 889 nM, with no activity against human G6PD. |
| PC-20586 |
ML304
PfG6PDH inhibitor
|
ML304 (ML 304) is a potent, selective inhibitor of Plasmodium falciparum glucose-6-phosphate dehydrogenase (PfG6PDH) with IC50 of 190 nM, with no activity against human G6PD (IC50=80 uM). |
| PC-35114 |
N205
|
N205 is a novel anti-malaria compound with in vitro IC50 of 1.3 nM against Plasmodium falciparum (3D7). |
| PC-63462 |
BKI-1369
|
BKI-1369 is an effective bumped kinase inhibitor (BKI), inhibits Theileria equi in vitro and reduces parasite burden and disease severity in the gnotobiotic pig model. |
| PC-63382 |
Tafenoquine succinate
|
Tafenoquine succinate (SB-252263, Tafenoquine, WR 238605) is a long-acting, orally active anti-malarial agent to prevent malaria that is holoendemic for Plasmodium falciparum.. |
| PC-63381 |
Tafenoquine
|
Tafenoquine (SB-252263, Tafenoquine, WR 238605) is a long-acting, orally active anti-malarial agent to prevent malaria that is holoendemic for Plasmodium falciparum.. |
