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Cat. No. Product Name Information
PC-24812

Ivermectin

CAS 70288-86-7

Ivermectin (MK-933) is a broad-spectrum anti-parasite agent, is a specific inhibitor ofimportin α/β-mediated nuclear import with potent antiviral activity towards both HIV-1 and DENV, also is a positive allosteric effector of P2X4 and α7 neuronal nicotinic acetylcholine receptor (nAChRs), also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import.
PC-24762

Endochin

T. gondii bc1 inhibitor

Endochin is an antimalarial agent, inhibits T. gondii growth in vitro (IC50=0.003 nM), inhibits  inhibited T.gondii cytochrome c reduction with IC50 of 8.2 nM.
PC-24761

ELQ-271

T. gondii bc1 inhibitor

ELQ-271 is a potent, orally bioavailable inhibitor of T. gondii growth in vitro (IC50=0.1 nM) and is effective against acute and latent toxoplasmosis in mice, inhibits cytochrome c reduction by the T. gondii cytochrome bc(1) complex.
PC-24760

ELQ-316

T. gondii bc1 inhibitor

ELQ-316 is a potent, orally bioavailable inhibitor of T. gondii growth in vitro (IC50=0.007 nM) and is effective against acute and latent toxoplasmosis in mice, inhibits cytochrome c reduction by the T. gondii cytochrome bc(1) complex.
PC-24725

TAO inhibitor 1

TAO inhibitor

TAO inhibitor 1 is a potent, selective trypanosome alternative oxidase (TAO) inhibitor with IC50/Ki of 1.3/3.46 nM (purified TAO), displays broad-spectrum activity against african animal trypanosomes.
PC-24700

PSAC inhibitor compound 2

PSAC channel inhibitor

PSAC inhibitor compound 2 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.9.
PC-24699

PSAC inhibitor compound 1

PSAC channel inhibitor

PSAC inhibitor compound 1 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.3.
PC-24372

WJM280

Pf cyt b inhibitor

WJM280 is a potent, specific inhibitor of P. falciparum mitochondrial protein cytochrome b (Pf cyt b), inhibits LDH activity of P. falciparum 3D7 parasites with EC50 of 40 nM.
PC-24371

WJM664

PfATP4 inhibitor

WJM664 is a small molecule inhibitor of P. falciparum malaria P-type ATPase 4 (PfATP4), inhibits P. falciparum 3D7 parasite growth with EC50 of 13 nM.
PC-23936

YAT2150

Protein aggregation inhibitor

YAT2150 is a potent antileishmanial compound and inhibitor of protein aggregation, exhibits potent antiplasmodial activity with IC50 of 90 nM.
PC-23895

MMV019918

Anti-malaria

MMV019918 is a specific small molecule inhibitor of trypanocidal cysteine protease, acts directly against the trypomastigote and the intracellular amastigote forms of T. cruzi at 3 μM.
PC-23894

MMV019017

Anti-malaria

MMV019017 is a small molecule anti-malaria compound, maybe inhibit PfATP4, an ATPase transporter located on the plasma membrane of the malaria parasite.

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