| Cat. No. |
Product Name |
Information |
| PC-60316 |
SCYX-7158
Anti-parasite
|
SCYX-7158 (AN-5568, Acoziborole) is an orally-active, CNS permeable benzoxaborole antiprotozoal agent. |
| PC-60315 |
GNF6702
T. cruzi proteasome inhibitor
|
GNF6702 (GNF 6702) is a selective, non-competitive inhibitor of the kinetoplastid proteasome, inhibits the chymotrypsin-like activity of the T. cruzi proteasome with IC50 of 35 nM. |
| PC-45381 |
Closantel sodium
FICD inhibitor
|
Closantel sodium is a veterinary anthelmintic with known proton ionophore activities, also is a small molecule inhibitor of the AMP transferase FICD with IC50 of 7.27 uM. |
| PC-45380 |
Closantel
FICD inhibitor
|
Closantel (FICD inhibitor C22) is a veterinary anthelmintic with known proton ionophore activities, also is a small molecule inhibitor of the AMP transferase FICD with IC50 of 7.27 uM. |
| PC-45409 |
Pyrimethamine
NRF2 inhibitor
|
Pyrimethamine (Pirimetamin, RP 4753) is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties, interferes with the regeneration of tetrahydrofolic acid from dihydrofolate by competitively inhibiting DHFR, also is a potent NRF2 inhibitor. |
| PC-42397 |
Emodepside
Anthelmintic
|
Emodepside (PF 1022-221) is a semisynthetic derivative of PF1022A, and novel cyclo-depsipeptide anthelmintic which is efficacious against a variety of gastrointestinal nematodes. |
| PC-45382 |
Rafoxanide
Antiparasite, SPAK inhibitor
|
Rafoxanide is a salicylanilide anthelmintic agent that also shows to be an allosteric inhibitor of SPAK and OSR1. |
| PC-45368 |
Buparvaquone
Antiprotozoal
|
Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone. |
| PC-45379 |
Mebendazole
|
Mebendazole is a highly effective, broad-spectrum antihelmintic by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells.. |
| PC-45158 |
Doramectin
Antibiotic
|
Doramectin is a derivative of ivermectin that approved for the treatment of parasites, is an active compound against S.mansoni in an NMRI mouse infection model. |
| PC-42044 |
NSC5844
Antimalarial
|
NSC5844 (RE-640) is a bis-quinoline with diverse biological activities, inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine with IC50 of 17 and 27 nM, respectively. |
| PC-27252 |
PfHsp70-1 inhibitor AMK4
PfHsp70-1 inhibitor
|
PfHsp70-1 inhibitor AMK4 is a selective inhibitor of Plasmodium falciparum chaperone PfHsp70-1 with MST Kd of 41 uM,binds to substrate-binding domain (SBD) and leads to disruption in peptide binding, has >25-fold for PfHsp70-1 over the human homolog HSPA1A. |
