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Cat. No. Product Name Information
PC-45368

Buparvaquone

Antiprotozoal

Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone.
PC-45379

Mebendazole

Mebendazole is a highly effective, broad-spectrum antihelmintic by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells..
PC-45158

Doramectin

Antibiotic

Doramectin is a derivative of ivermectin that approved for the treatment of parasites, is an active compound against S.mansoni in an NMRI mouse infection model.
PC-25444

Schistosome p97 inhibitor 739

Parasite p97 inhibitor

Schistosome p97 inhibitor 739 is a potent, selective and covalent inhibitor of parasite p97 with IC50 of 150 nM and 320 nM for S. mansoni and H. sapiens p97 respectively.
PC-25438

Clocinizine

Antiparasite

Clocinizine is a chlorinated analogue of cinnarizine, shows potent antischistosomal activity against both male and female parasites with EC50 and EC90 of 4.6 uM and 5.9 uM respectively.
PC-25297

Fexinidazole

T. brucei inhibitor

Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent, shows trypanocidal activity against T. brucei subspecies and strains with IC50 of 0.7-3.3 uM, has the potential for human sleeping sickness (HAT) caused by infection with T. brucei.
PC-25293

LXE408

Kinetoplastid proteasome inhibitor

LXE408 is a potent, selective inhibitor of the kinetoplastid proteasome with IC50 of 0.04 uM (L. donovani proteasome), inhibits L. donovani amastigote proliferation within primary mouse macrophages (IC50=0.04 uM).
PC-25292

DNDI-VL-2098

Visceral leishmaniasis inhibitor

DNDI-VL-2098 is an orally effective preclinical drug candidate for visceral leishmaniasis (VL) with IC50 of 0.17 uM for L. infantum.
PC-25291

DNDI-0690

Visceral leishmaniasis inhibitor

DNDI-0690 is a clinical drug candidate for visceral leishmaniasis (VL), demonstrated excellent in vitro activity against three Old World and three New World cutaneous Leishmania strains (EC50<5 uM).
PC-25290

DNDI-5561

T. cruzi inhibitor

DNDI-5561 is a small molecule inhibitor of T. cruzi and L. infantum with IC50 of 38 uM and 0.2 uM.
PC-25202

BKI-1841

CpCDPK1 inhibitor

BKI-1841 is a highly potent, specific Cryptosporidium calcium-dependent protein kinase 1 (CDPK1) inhibitor with IC50 of 3 nM (CpCDPK1, C. parvum CDPK1) and EC50 of 0.7 uM against C. parvum parasites in Nanoluciferase assays.
PC-25201

BKI-1770

CpCDPK1 inhibitor

BKI-1770 is a highly potent, specific Cryptosporidium calcium-dependent protein kinase 1 (CDPK1) inhibitor with IC50 of 2 nM (CpCDPK1, C. parvum CDPK1) and EC50 of 0.5 uM against C. parvum parasites in Nanoluciferase assays.

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