| Cat. No. |
Product Name |
Information |
| PC-24760 |
ELQ-316
T. gondii bc1 inhibitor
|
ELQ-316 is a potent, orally bioavailable inhibitor of T. gondii growth in vitro (IC50=0.007 nM) and is effective against acute and latent toxoplasmosis in mice, inhibits cytochrome c reduction by the T. gondii cytochrome bc(1) complex. |
| PC-24759 |
BKI-1748
CDPK1 inhibitor
|
BKI-1748 a small molecule bumped kinase inhibitor targeting calcium dependent protein kinase 1 (CDPK1), inhibits TgCDPK1 and NcCDPK1 enzyme activities at low nM-concentrations, inhibits proliferation of apicomplexan parasites with EC50 of 165 nM for N. caninum and 43 nM for T. gondii. |
| PC-24725 |
TAO inhibitor 1
TAO inhibitor
|
TAO inhibitor 1 is a potent, selective trypanosome alternative oxidase (TAO) inhibitor with IC50/Ki of 1.3/3.46 nM (purified TAO), displays broad-spectrum activity against african animal trypanosomes. |
| PC-24700 |
PSAC inhibitor compound 2
PSAC channel inhibitor
|
PSAC inhibitor compound 2 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.9. |
| PC-24699 |
PSAC inhibitor compound 1
PSAC channel inhibitor
|
PSAC inhibitor compound 1 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.3. |
| PC-24372 |
WJM280
Pf cyt b inhibitor
|
WJM280 is a potent, specific inhibitor of P. falciparum mitochondrial protein cytochrome b (Pf cyt b), inhibits LDH activity of P. falciparum 3D7 parasites with EC50 of 40 nM. |
| PC-24371 |
WJM664
PfATP4 inhibitor
|
WJM664 is a small molecule inhibitor of P. falciparum malaria P-type ATPase 4 (PfATP4), inhibits P. falciparum 3D7 parasite growth with EC50 of 13 nM. |
| PC-23936 |
YAT2150
Protein aggregation inhibitor
|
YAT2150 is a potent antileishmanial compound and inhibitor of protein aggregation, exhibits potent antiplasmodial activity with IC50 of 90 nM. |
| PC-23895 |
MMV019918
Anti-malaria
|
MMV019918 is a specific small molecule inhibitor of trypanocidal cysteine protease, acts directly against the trypomastigote and the intracellular amastigote forms of T. cruzi at 3 μM. |
| PC-23894 |
MMV019017
Anti-malaria
|
MMV019017 is a small molecule anti-malaria compound, maybe inhibit PfATP4, an ATPase transporter located on the plasma membrane of the malaria parasite. |
| PC-23893 |
PRC1590
P.falciparum inhibitor
|
PRC1590 is a tetrahydro-β-carboline compound that potently kills the malaria parasite with EC50 of 145 nM and 142 nM in growth inhibition assays in 3D7WT and Dd2 strains. |
| PC-23720 |
DSM705 hydrochloride
DHODH inhibitor
|
DSM705 hydrochloride (DSM 705) is a potent, highly selective, long-duration and orally bioavailable malaria DHODH inhibitor with IC50 of 95 nM (PfDHODH), and 52 nM (P. vivax DHODH). |
