Cat. No. |
Product Name |
Information |
PC-38540 |
Soporidine
|
Soporidine is a small-molecule antagonist of germination of the parasitic plant Striga hermonthica, specifically inhibits S. hermonthica strigolactone receptor and inhibits the parasite germination, disrupting the Striga lifecycle. |
PC-38537 |
NCGC00262650
AMA1-RON2 inhibitor
|
NCGC00262650 is a small molecule merozoite invasion inhibitor inhibitor of parasite AMA1-RON2 interaction, blocks entry of merozoites into RBCs with IC50 of 9.8 uM. |
PC-38416 |
MMV688533
Antimalarial
|
MMV688533 is a potent antimalarial compound that displays fast parasite clearance in vitro and is not cross-resistant with known antimalarials, MMV688533 is highly potent against multiple P. falciparum strains with IC50 values in low nanomolar range (P. falciparum 3D7, IC50=1.9 nM). |
PC-38402 |
Mivorilaner
Parasiticidal agent
|
Mivorilaner is a parasiticidal dihydroisoxazole compound. |
PC-38367 |
Modoflaner
Antiparasitic agent
|
Modoflaner is an antiparasitic agent. |
PC-38359 |
Fanotaprim
TgDHFR inhibitor
|
Fanotaprim (VYR-006) is a potent, selective Toxoplasma gondii DHFR (TgDHFR) inhibitor with IC50 of 1.6 nM, 200-fold selectivity over human DHFR (hDHFR), shows anti-parasiticidal activity in vitro and in vivo. |
PC-73100 |
MMV675968
Antifungal agent
|
MMV675968 is a potent, small molecule inhibitor of Toxoplasma gondii (T. gondii) with IC50 of 0.02 uM, via the pathogen box. |
PC-72859 |
PDE-I2
Anti-malaria
|
PDE-I2 is a potent and selective inhibitor of malaria proliferation with Pf IC50 of 18 nM. |
PC-72540 |
MMV084978
PfAcAS inhibitor
|
MMV084978 (MMV 084978) is an antiplasmodial drug-like compound tageting Plasmodium falciparum acetyl-coenzyme A synthetase (PfAcAS), directly and selectively inhibit PfAcAS activity in vitro with IC50 of 370 nM. |
PC-72539 |
MMV019721
PfAcAS inhibitor
|
MMV019721 (MMV019721) is an antiplasmodial drug-like compound tageting Plasmodium falciparum acetyl-coenzyme A synthetase (PfAcAS), directly and selectively inhibit PfAcAS activity in vitro with IC50 of 73 nM. |
PC-72407 |
CTN1122
L-CK1.2 inhibitor
|
CTN1122 (CTN-1122) is a potent, selective Leishmaniacasein kinase 1 isoform 2 (CK1.2, L-CK1.2) with IC50 of 0.72 uM (LmCK1) and 0.8 uM (amastigotes L. major), antileishmanial compound. |
PC-72339 |
MMV030084
Pf PKG inhibitor
|
MMV030084 (MMV-030084) is a potent, specific P. falciparum cGMP-dependent protein kinase (PKG) inhibitor (Kdapp=9-16 nM), inhibits invasion of P. berghei ANKA parasites into HepG2 liver cells with IC50 of 199 nM. |