| Cat. No. |
Product Name |
Information |
| PC-47069 |
NPD-008
TbrPDEB1 inhibitor
|
NPD-008 is a potent, selective Trypanosoma brucei PDE B1 (TbrPDEB1) inhibitor with Ki of 100 nM, exhibits antitrypanosomal effects with IC50 of 5.5 uM. |
| PC-47035 |
UBMC-4
T. cruzi inhibitor
|
UBMC-4 is a potential Trypanosoma cruzi AKT-like pleckstrin homology (PH) domain, exhibits trypanocidal effect on T. cruzi amastigotes with EC50 of 1.85 uM (0.774 ug/mL). |
| PC-47013 |
GNF179
Antimalarial
|
GNF179 is an antimalarial imidazolopiperazine, possesses low nanomolar potency against P. falciparum liver stages, asexual blood stages and sexual stage gametocytes. |
| PC-38663 |
MMV665916
PfFT inhibitor
|
MMV665916 is potential antimalarial agent targeting the P. falciparum farnesyltransferase (PfFT), shows remarkable growth inhibition with EC50 value of 0.4 uM. |
| PC-38540 |
Soporidine
|
Soporidine is a small-molecule antagonist of germination of the parasitic plant Striga hermonthica, specifically inhibits S. hermonthica strigolactone receptor and inhibits the parasite germination, disrupting the Striga lifecycle. |
| PC-38537 |
NCGC00262650
AMA1-RON2 inhibitor
|
NCGC00262650 is a small molecule merozoite invasion inhibitor inhibitor of parasite AMA1-RON2 interaction, blocks entry of merozoites into RBCs with IC50 of 9.8 uM. |
| PC-38416 |
MMV688533
Antimalarial
|
MMV688533 is a potent antimalarial compound that displays fast parasite clearance in vitro and is not cross-resistant with known antimalarials, MMV688533 is highly potent against multiple P. falciparum strains with IC50 values in low nanomolar range (P. falciparum 3D7, IC50=1.9 nM). |
| PC-38402 |
Mivorilaner
Parasiticidal agent
|
Mivorilaner is a parasiticidal dihydroisoxazole compound. |
| PC-38367 |
Modoflaner
Antiparasitic agent
|
Modoflaner is an isophenylamide insecticide. Modoflaner may act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels |
| PC-38359 |
Fanotaprim
TgDHFR inhibitor
|
Fanotaprim (VYR-006) is a potent, selective Toxoplasma gondii DHFR (TgDHFR) inhibitor with IC50 of 1.6 nM, 200-fold selectivity over human DHFR (hDHFR), shows anti-parasiticidal activity in vitro and in vivo. |
| PC-73100 |
MMV675968
Antifungal agent
|
MMV675968 is a potent, small molecule inhibitor of Toxoplasma gondii (T. gondii) with IC50 of 0.02 uM, via the pathogen box. |
| PC-73056 |
TCMDC-135051
PfCLK3 inhibitor
|
TCMDC-135051 is a potent PfCLK3 inhibitor with IC50 of 40 nM. |
