Cat. No. |
Product Name |
Information |
PC-49168 |
PAV-206
HIV-1 inhibitor
|
PAV-206 is a novel potent antiretroviral chemotype that inhibits HIV-1 replication with EC50 of 34 nM in HIV-1-infected MT-2 T cells, and 75 nM in HIV-1-infected peripheral blood mononuclear cells (PBMCs), inhibits HIV-1 replication by interfering with HIV-1 assembly. |
PC-49139 |
RO-0335
NNRTI
|
RO-0335 is a highly potent, selective nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 with IC50 of 8.1 nM, potently inhibits HIV replication with IC50 of 1.3 nM in cell based assays. |
PC-38861 |
SO-7g
NNRTI
|
SO-7g is a novel highly active HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI), exhibits moderate to excellent potency against wild-type HIV-1 with EC50 of 5.3 nM. |
PC-38563 |
Temsavir
HIV-1 attachment inhibitor
|
Temsavir (BMS-626529) is a highly potent, small molecule HIV-1 attachment inhibitor with IC50 values of 2.26 nM, 0.34 nM and 1.3 nM for HIV-1 subtype A, B, and C envelope, repectively. |
PC-73436 |
Pirmitegravir
HIV-1 integrase inhibitor
|
Pirmitegravir is a highly potent, first-in-class, allosteric HIV-1 integrase inhibitor (ALLINI), targets LEDGF/p75 binding site, displays picomolar IC50 antiviral potency in human PBMCs. |
PC-73248 |
FD028
HIV-1 inactivator
|
FD028 is a small-molecule HIV-1 inactivator by conjugating FD016 (gp120-CD4 binding inhibitor) with FD017 (HIV-1 fusion inhibitor), inactivates cell-free virions (IC50=0.7 uM) of by targeting both HIV-1 gp120 and gp41. |
PC-73247 |
S2C3
HIV entry inhibitor
|
S2C3 is a small molecule HIV-1 fusion inhibitor, targets the membrane proximal external region (MPER) of HIV-1 envelope spike. |
PC-72683 |
GSK3739936
HIV-1 integrase inhibitor
|
GSK3739936 (BMS-986180) is a potent, allosteric HIV-1 integrase (ALLINI), shows excellent potency in vitro against majority of the 124/125 variants (EC50=1.7 nM). |
PC-72633 |
HIV-1 Integrase inhibitor GS-B
HIV-1 integrase inhibitor
|
HIV-1 Integrase inhibitor GS-B (GS-B) is a novel non-catalytic site integrase inhibitor of HIV-1 integrase (IN), inhibits the interaction between LEDGF IBD and IN with IC50 of 8.1 nM. |
PC-72632 |
JTP-0157602
HIV-1 integrase inhibitor
|
JTP-0157602 (JTP0157602) is a novel non-catalytic site integrase inhibitor of HIV-1 integrase (IN), inhibits the interaction between LEDGF IBD and IN with IC50 of 4.2 nM. |
PC-72614 |
NBD-14270
HIV-1 gp120 inhibitor
|
NBD-14270 (NBD14270) is an HIV-1 gp120 antagonist, shows antiviral activity against HIV-1HXB2 with IC50 of 180 nM. |
PC-72601 |
GSK3640254
HIV-1 maturation inhibitor
|
GSK3640254 (GSK254, Fipravirimat) is a novel potent HIV-1 maturation inhibitor with EC90 of 33 nM against a minilibrary of clinically relevant HIV-1 polymorphisms in a multiple-cycle assay. |