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Cat. No. Product Name Information
PC-49251

ELR510444

Microtubule disruptor

ELR510444 (ELR-510444) is a small molecule microtubule disruptor that directly interacts with tubulin at the colchicine-binding site, shows potent microtubule-disrupting activity.
PC-49013

CH-3-8

Microtubule destabilizer

CH-3-8 is a novel microtubule polymerization inhibitor with little susceptible to transporter-mediated chemoresistance, binds to the colchicine-binding site in tubulin protein, disrupts microtubule dynamics at the nanomolar concentration in MIA PaCa-2 and PANC-1 pancreatic cancer cell lines.
PC-49011

QW-296

Microtubule destabilizer

QW-296 is a novel microtubule destabilizer with little susceptible to transporter-mediated drug resistance, disturbs the microtubule dynamics at the nanomolar concentration in A375 and B16F10 melanoma cells.
PC-47072

R-huezole

Tubulin modulator

R-huezole is a phase-separating small molecule that forms liquid droplets to selectively sequester tubulin, enters cultured human cells and prevents cell mitosis by forming tubulin-concentrating condensates in cells.
PC-38804

CH-2-77 analogue 60c

Tubulin inhibitor

CH-2-77 analogue 60c is a potent colchicine-binding site tubulin inhibitor, inhibits tubulin polymerization and is effective against P-glycoprotein-mediated multiple drug resistance and taxol resistance.
PC-38803

CH-2-77

Tubulin inhibitor

CH-2-77 is a potent colchicine-binding site inhibitor (CBSI) targeting tubulin, shows potent anti-proliferative activity against a panel of cancer cells in vitro and efficacious anti-tumor effects in vivo.
PC-38698

ALM201

Angiogenesis inhibitor, FKBP ligand

ALM201 is a small 23 amino acid peptide derived from the FK506 binding protein FKBPL, a targeted microtubule binding agent which exhibits potent anti-angiogenic activity in vitro and in vivo.
PC-38550

Todalam

Tubulin inhibitor

Todalam is a novel small molecule tubulin inhibitor with IC50 of 8.8 uM against HeLa cells, fully inhibits microtubule formation with IC50 of 48 uM, acting as a reversible microtubule-destabilizing agent in vitro and in cells.
PC-72562

Microtubule inhibitor PP-13

Microtubule inhibitor

Microtubule inhibitor PP-13 is a novel microtubule-destabilizing agent, directly inhibits microtubule assembly by targeting the colchicine-binding site in β-tubulin.
PC-72275

IMB5476

Microtubule inhibitor

IMB5476 (IMB 5476) is a nitrobenzoate microtubule inhibitor, exerts broad-spectrum cytotoxicity against various human tumor cell lines (NCI-H460, IC50=144 nM).
PC-72173

PST-3

Microtubule inhibitor

PST-3 (Microtubule inhibitor PST-3) is a novel microtubule inhibitor exhibited broad-spectrum cellular cytotoxicity and in vivo potency with high safety.
PC-38002

PCH-1

Tubulin inhibitor

PCH-1 is a potent antitumor agent that disrupts microtubule assembly, leading to cancer cell death, interacts vinblastine binding site on tubulin.

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