| Cat. No. |
Product Name |
Information |
| PC-23419 |
Mavorixafor trihydrochloride
CXCR4 antagonist
|
Mavorixafor trihydrochloride (AMD-070, AMD-11070) is a potent and selective antagonist of CXCR4 with IC50 of 13 nM in a CXCR4 125I-SDF inhibition binding assay. |
| PC-23312 |
DZH2
CCR5/CXCR4 inhibitor
|
DZH2 is a dual inhibitor of the chemokine receptors CCR5 and CXCR4 with IC50 of 8.7/13.7 uM in Ca2+-mobilization assays. |
| PC-23198 |
ZK756326 dihydrochloride
CCR8 agonist
|
ZK756326 dihydrochloride is a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8, inhibits the binding of the CCR8 ligand I-309 (CCL1) with IC50 of 1.8 uM. |
| PC-23096 |
CXCR3 antagonist 7D
CXCR3 antagonist
|
CXCR3 antagonist 7D is a specific small molecule CXCR3 antagonist, inhibits CXCL4-mediated DENV2 replication with EC50 of 2.1 uM in monocytic U937-DC-SIGN cells. |
| PC-23013 |
OXM2
CCR6 inhibitor
|
OXM2 is a highly selective, allosteric antagonist of CCR6, inhibits CCL20-mediated CCR6+ human T-cell chemotaxis with pIC50 of 6.78. |
| PC-23012 |
OXM1
CCR6 inhibitor
|
OXM1 is a highly selective, allosteric antagonist of CCR6, inhibits CCL20-mediated CCR6+ human T-cell chemotaxis with pIC50 of 6.8. |
| PC-23011 |
SQA1
CCR6 inhibitor
|
SQA1 is a small molecule allosteric antagonist of CCR6, inhibits CCL20-mediated CCR6+ human T-cell chemotaxis with pIC50 of 6.7, also inhibits CXCR2. |
| PC-22933 |
LIH383
ACKR3 agonist
|
LIH383 is a potent, selective atypical chemokine receptor ACKR3 (CXCR7) agonist with EC50 of 0.61 nM in inducing β-arrestin recruitment to ACKR3. |
| PC-22932 |
TC14012
ACKR3 agonist
|
TC14012 is a selective and peptidomimetic CXCR4 antagonist with IC50 of 19.3 nM, also is a specific CXCR7 (ACKR3) agonist with EC50 of 350 nM for recruiting β-arrestin 2 to CXCR7. |
| PC-22931 |
LN5972
ACKR3 agonist
|
LN5972 (LN-5972) is a potent, selective and first-in-class agonist of the atypical chemokine receptor 3 (ACKR3, CXCR7) with β-arrestin EC50 of 3.4 uM. |
| PC-22930 |
ACKR3 agonist 27
ACKR3 agonist
|
ACKR3 agonist 27 is a potent, selective small molecule agonist of atypical chemokine receptor ACKR3 (CXCR7) with EC50 of 69 nM in β-arrestin recruitment assays, Emax=82%. |
| PC-22322 |
IDOR-1117-2520
CCR6 inhibitor
|
IDOR-1117-2520 is a potent, selective CCR6 antagonist with IC50 of 62.9 nM for CCL20-mediated calcium flow inhibition in FLIPR calcium mobilization assay. |
