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Cat. No. Product Name Information
PC-38487

VUF11418

CXCR3 agonist

VUF11418 is a selective, nonpeptidomimetic agonist of CXCR3 with binding pKi vaule of 7.2, pEC50 value of 6.0 in [35S]GTPγS functional assays.
PC-73267

AMD3451

CXCR5/CXCR4 antagonist

AMD3451 is a specific, dual CXCR5/CXCR4 antagonist with antiviral activity against a wide variety of HIV-1 and HIV-2 (IC50=1.2 to 26.5 uM) in vitro.
PC-73266

AstraZeneca CCR4 antagonist

CCR4 antagonist

AstraZeneca CCR4 antagonist is a potent, selective CCR4 antagonist, inhibits CCR4 ligand macrophage-derived chemokine (MDC/CCL22) in CCR4+CD4+ T cells.
PC-73265

RS-1748

CCR4 antagonist

RS-1748 is a highly potent, selective, orallu active CCR4 antagonist, inhibits [125I]CCL17 binding to human CCR4 with IC50 of 27.7 nM.
PC-73264

RS-1269

CCR4 antagonist

RS-1269 is a highly potent, selective CCR4 antagonist, inhibits [125I]CCL17 binding to human CCR4 with IC50 of 27.7 nM.
PC-73263

CCR4-IN-22

CCR4 antagonist

CCR4-IN-22 (Compound 22) is a potent, selective CCR4 antagonist with IC50 of 20 nM, efficiently inhibits CCR4-mediated Ca2+ mobilization and chemotaxis in vitro with IC50 of 3 and 7 nM, repectively.
PC-73262

GSK2239633A

CCR4 antagonist

GSK2239633A is a potent, allosteric CC-chemokine receptor 4 (CCR4) antagonist with pIC50 of 7.83 in 35S-GTPγS competition assay.
PC-73171

USL311

CXCR4 inhibitor

USL311 is a potent, selective, orally bioavailable CXCR4 antagonist, with potential antineoplastic activity.
PC-73125

SX-682

CXCR 1/2 inhibitor

SX-682 (SX682) is a potent, allosteric, orally bioavailable inhibitor of CXCR1 and CXCR2.
PC-72032

HF50731

CXCR4 antagonist

HF50731 (HF-50731) is a novel potent, selective CXCR4 antagonist with Ki of 19.8 nM in the CXCR4 competitive binding assay.
PC-35230

GW-766994 R-form

GW-766994 (GW766994) is a potent, selective, orally available CCR3 antagonist with pKi of 7.86 for inhibiting eotaxin-induced eosinophil chemotaxis in vitro assays.
PC-42890

BX471 hydrochloride

BX471 is a potent, selective, orally available CCR1 antagonist with Ki of 1 nM for hCCR1, displays 100 times less affinity for rat CCR1.

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