| Cat. No. |
Product Name |
Information |
| PC-61090 |
GSK 163929
CCR5 antagonist
|
GSK 163929 is a potent, selective CCR5 antagonist and HIV-1 entry inhibitor with pIC50 of 8.37 and 8.46 in HOS and PBL assays, respectively. |
| PC-61089 |
GSK 214096
CCR5 antagonist
|
GSK 214096 potent, selective CCR5 antagonist and HIV-1 entry inhibitor, inhibits HIV-1 glycoprotein 120 (gp120) binds to the CD4+ T-cell receptor. |
| PC-60972 |
LMD-009
CCR8 agonist
|
LMD-009 (LMD 009, LMD009) is a potent, selective, nonpeptide CCR8 agonist that stimulates CCR8-mediated chemotaxis, inositol phosphate accumulation and calcium release with EC50 of 11-87 nM. |
| PC-60855 |
LMD-A
|
LMD-A (CCR8 antagonist LMD-A) is a highly potent, small molecule antagonist of chemokine receptor CCR8 with EC50 of 2.5 nM. |
| PC-60779 |
E 6130
CX3CR1 inhibitor
|
E6130 is a potent, selective, orally available CX3C chemokine receptor 1 (CX3CR1) modulator that inhibits the fractalkine-induced chemotaxis of human peripheral blood NK cells with IC50 of 4.9 nM. |
| PC-60672 |
INCB9471
CCR5 antagonist
|
INCB9471 is a potent, selective and orally bioavailable CCR5 antagonist IC50 of 6.5 nM, Kd of 3.1 nM in human PBMCs. |
| PC-60626 |
CX797
CXCR2 antagonist
|
CX797 is a potent, specfic CXCR2 antagonist that inhibits IL8 down-regulation of forskolin-induced cAMP with IC50 of 7.79 uM. |
| PC-60625 |
CX815
CXCR2 antagonist
|
CX815 (NSC 120213) is a potent, selective CXCR2 inhibitor with IC50 of 0.4 nM. |
| PC-60624 |
CX4152
CXCR2 antagonist
|
CX4152 is a potent, selective CXCR2 inhibitor with IC50 of 7.6 nM, displays>1,000-fold selectivity over CXCR4 (IC50>50 uM). |
| PC-60623 |
CX4338
CXCR2 antagonist
|
CX4338 (CX-4338) is a potent, selective CXCR2 inhibitor that selectively inhibits CXCR2-mediated recruitment of β-arrestin-2 with IC50 of 6.3 uM. |
| PC-60622 |
SB-332235
CXCR2 antagonist
|
SB332235 (SB-332235) is a potent, selective and competitive CXCR2 inhibitor that selectively inhibits CXCR2-mediated recruitment of β-arrestin-2 with pKi of 8.92. |
| PC-60621 |
SB 265610
CXCR2 antagonist
|
SB 265610 is a potent, selective, reversible CXCR2 antagonist with with Kd of 3.48 nM. |
