| Cat. No. |
Product Name |
Information |
| PC-35036 |
BMS-817399
CCR1 inhibitor
|
BMS-817399 is a potent, selective, orally bioavailable CCR1 antagonist with binding IC50 of 1 nM, inhibits MIP-1α-induced chemotaxis with IC50 of 6 nM. |
| PC-35030 |
BI 6901
CCR10 antagonist
|
BI 6901 is a potent, selective CCR10 antagonist with Aequorin Ca2+ flux pIC50 of 9.0, shows high selectivity over other GPCRs. |
| PC-35029 |
CCR10 antagonist 1
|
CCR10 antagonist 1 is a potent, selective CCR10 antagonist with IC50 of 690 nM. |
| PC-63566 |
BMS-457
CCR1 inhibitor
|
BMS-457 is a potent and selective CCR1 antagonist with binding IC50 of 0.8 nM, >1,000-fold selectivity against other CC family receptors. |
| PC-43512 |
TAK-779
CCR5 antagonist
|
TAK-779 (TAK779) is a potent, specific, nonpeptide CCR5 antagonist with Kd of 0.45 nM, antagonizes CCR2b to a lesser extent (27 nM) but does not affect CCR1, CCR3, or CCR4. |
| PC-63440 |
R243
CCR8 antagonist
|
R243 is a potent, small molecule CCR8 antagonist that inhibits CCR8 signaling and chemotaxis, inhibits CCL1-induced Ca2+ flux and CCL1-driven peritoneal macrophages aggregation at 0.2 uM. |
| PC-42890 |
BX471 hydrochloride
CCR1 antagonist
|
BX471 is a potent, selective, orally available CCR1 antagonist with Ki of 1 nM for hCCR1, displays 100 times less affinity for rat CCR1. |
| PC-42889 |
BX471
CCR1 inhibitor
|
BX471 (BX-471) is a potent, selective, non-peptide CCR1 antagonist with Ki of 1 nM for hCCR1, displays 100 times less affinity for rat CCR1. |
| PC-62992 |
Aplaviroc hydrochloride
CCR5 inhibitor
|
Aplaviroc hydrochloride (GSK-873140;GW 873140;AK-602;ONO-4128) is a potent, noncompetitive, allosteric antagonist of the CCR5 receptor with pKb of 8.6. |
| PC-62990 |
Elubrixin tosylate
CXCR2 antagonist
|
Elubrixin tosylate (SB-656933, GSK656933) is a potent, selective, competitive and reversible CXCR2 antagonist. |
| PC-62989 |
Elubrixin
CXCR2 antagonist
|
Elubrixin (SB-656933, GSK656933) is a potent, selective, competitive and reversible CXCR2 antagonist. |
| PC-62775 |
CXCR2 inhibitor 68
CXCR2 antagonist
|
CXCR2-IN-68 is a potent, selective, brain penetrant, and orally bioavailable CXCR2 antagonist with pIC50 of 9.0, displays 730-fold selectivity over CXCR1 and >1,900-fold selectivity over all other chemokine receptors. |
