| Cat. No. |
Product Name |
Information |
| PC-60325 |
JNJ-27141491
CCR2 antagonist
|
JNJ-27141491 is a potent, selective, noncompetitive, orally active CCR2 antagonist with IC50 of 172 nM. |
| PC-60324 |
BMS-22
CCR2 antagonist
|
BMS-22 is a potent, selective, allosteric CCR2 antagonist with binding IC50 of 5.1 nM. |
| PC-60323 |
CCR2-RA-[R]
CCR2 antagonist
|
CCR2-RA-[R] is a potent, selective, allosteric CCR2 antagonist with IC50 of 103 nM. |
| PC-60322 |
BMS-687681
CCR2/5 inhibitor
|
BMS-687681 (BMS-681) is a potent and orally bioavailable dual antagonist of CCR2 and CCR5 with binding IC50 of 0.7 nM and 2.4 nM, respectively. |
| PC-60261 |
Chalcone 4 hydrate
CXCL12 inhibitor
|
Chalcone 4 hydrate is a potent, selective inhibitor of CXCL12 binding to CXCR4 and CXCR7 with IC50 of 200 nM. |
| PC-60260 |
VUF11403
CXCR7 agonist
|
VUF11403 is a potent CXCR7 (ACKR3) agonist with pKi of 8.1 (hCXCR7), induces recruitment of β-arrestin2 and subsequent internalization of CXCR7. |
| PC-60259 |
VUF11207 fumarate
CXCR7 agonist
|
VUF11207 fumarate is a potent CXCR7 (ACKR3) agonist with EC50 of 1.6 nM, inducse recruitment of β-arrestin2 and subsequent internalization of CXCR7 in cells. |
| PC-60244 |
(S)-CCX-777
CXCR7 agonist
|
(S)-CCX-777 is a small-molecule partial agonist of CXCR7 (ACKR3).. |
| PC-60243 |
(R)-CCX-777
CXCR7 agonist
|
(R)-CCX-777 is a small-molecule partial agonist of CXCR7 (ACKR3), the (R)-form of CCX777. |
| PC-60242 |
CCX-777
CXCR7 agonist
|
CCX-777 is a small-molecule partial agonist of CXCR7 (ACKR3). |
| PC-60240 |
CCX2553
CCR6 antagonist
|
CCX2553 is a potent and specific CCR6 antagonist. |
| PC-60212 |
CCX-771
CXCR7 inhibitor
|
CCX-771 is a potent, selective CXCR7 antagonist with IC50 of 4.1 nM. |
